PDB entry 2nx5

View 2nx5 on RCSB PDB site
Description: Crystal structure of ELS4 TCR bound to HLA-B*3501 presenting EBV peptide EPLPQGQLTAY at 1.7A
Class: immune system
Keywords: TCR-pMHC, immune complex, IMMUNE SYSTEM
Deposited on 2006-11-16, released 2007-02-27
The last revision prior to the SCOPe 2.05 freeze date was dated 2010-04-28, with a file datestamp of 2010-04-23.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.272
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla-b35
    Species: Homo sapiens [TaxId:9606]
    Gene: B-3501
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2nx5a1, d2nx5a2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2nx5b_
  • Chain 'C':
    Compound: EBV peptide, EPLPQGQLTAY
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2NX5 (0-10)
  • Chain 'D':
    Compound: ELS4 TCR alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2NX5 (0-187)
  • Chain 'E':
    Compound: ELS4 TCR beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2NX5 (0-242)
  • Chain 'F':
    Compound: hla-b35
    Species: Homo sapiens [TaxId:9606]
    Gene: B-3501
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2nx5f1, d2nx5f2
  • Chain 'G':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2nx5g_
  • Chain 'H':
    Compound: EBV peptide, EPLPQGQLTAY
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2NX5 (0-10)
  • Chain 'I':
    Compound: ELS4 TCR alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2NX5 (0-187)
  • Chain 'J':
    Compound: ELS4 TCR beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2NX5 (0-242)
  • Chain 'K':
    Compound: hla-b35
    Species: Homo sapiens [TaxId:9606]
    Gene: B-3501
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2nx5k1, d2nx5k2
  • Chain 'L':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2nx5l_
  • Chain 'M':
    Compound: EBV peptide, EPLPQGQLTAY
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2NX5 (0-10)
  • Chain 'N':
    Compound: ELS4 TCR alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2NX5 (0-187)
  • Chain 'P':
    Compound: ELS4 TCR beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2NX5 (0-242)
  • Chain 'Q':
    Compound: hla-b35
    Species: Homo sapiens [TaxId:9606]
    Gene: B-3501
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2nx5q1, d2nx5q2
  • Chain 'R':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2nx5r_
  • Chain 'S':
    Compound: EBV peptide, EPLPQGQLTAY
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2NX5 (0-10)
  • Chain 'T':
    Compound: ELS4 TCR alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2NX5 (0-187)
  • Chain 'U':
    Compound: ELS4 TCR beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2NX5 (0-242)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2nx5A (A:)
    gshsmryfytamsrpgrgeprfiavgyvddtqfvrfdsdaasprteprapwieqegpeyw
    drntqifktntqtyreslrnlrgyynqseagshiiqrmygcdlgpdgrllrghdqsaydg
    kdyialnedlsswtaadtaaqitqrkweaarvaeqlrayleglcvewlrrylengketlq
    radppkthvthhpvsdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdrt
    fqkwaavvvpsgeeqrytchvqheglpkpltlrwep
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2nx5B (B:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2nx5F (F:)
    gshsmryfytamsrpgrgeprfiavgyvddtqfvrfdsdaasprteprapwieqegpeyw
    drntqifktntqtyreslrnlrgyynqseagshiiqrmygcdlgpdgrllrghdqsaydg
    kdyialnedlsswtaadtaaqitqrkweaarvaeqlrayleglcvewlrrylengketlq
    radppkthvthhpvsdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdrt
    fqkwaavvvpsgeeqrytchvqheglpkpltlrwep
    

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2nx5G (G:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'H':
    No sequence available.

  • Chain 'I':
    No sequence available.

  • Chain 'J':
    No sequence available.

  • Chain 'K':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2nx5K (K:)
    gshsmryfytamsrpgrgeprfiavgyvddtqfvrfdsdaasprteprapwieqegpeyw
    drntqifktntqtyreslrnlrgyynqseagshiiqrmygcdlgpdgrllrghdqsaydg
    kdyialnedlsswtaadtaaqitqrkweaarvaeqlrayleglcvewlrrylengketlq
    radppkthvthhpvsdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdrt
    fqkwaavvvpsgeeqrytchvqheglpkpltlrwep
    

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2nx5L (L:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'M':
    No sequence available.

  • Chain 'N':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'Q':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2nx5Q (Q:)
    gshsmryfytamsrpgrgeprfiavgyvddtqfvrfdsdaasprteprapwieqegpeyw
    drntqifktntqtyreslrnlrgyynqseagshiiqrmygcdlgpdgrllrghdqsaydg
    kdyialnedlsswtaadtaaqitqrkweaarvaeqlrayleglcvewlrrylengketlq
    radppkthvthhpvsdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdrt
    fqkwaavvvpsgeeqrytchvqheglpkpltlrwep
    

  • Chain 'R':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2nx5R (R:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'S':
    No sequence available.

  • Chain 'T':
    No sequence available.

  • Chain 'U':
    No sequence available.