PDB entry 2nmp

View 2nmp on RCSB PDB site
Description: Crystal structure of human Cystathionine gamma lyase
Class: lyase
Keywords: amino-acid biosynthesis, lyase, pyridoxal phopshate, structural genomics, Structural Genomics Consortium, SGC
Deposited on 2006-10-23, released 2006-11-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.18
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cystathionine gamma-lyase
    Species: Homo sapiens [TaxId:9606]
    Gene: CTH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2nmpa_
  • Chain 'B':
    Compound: Cystathionine gamma-lyase
    Species: Homo sapiens [TaxId:9606]
    Gene: CTH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2nmpb_
  • Chain 'C':
    Compound: Cystathionine gamma-lyase
    Species: Homo sapiens [TaxId:9606]
    Gene: CTH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2nmpc_
  • Chain 'D':
    Compound: Cystathionine gamma-lyase
    Species: Homo sapiens [TaxId:9606]
    Gene: CTH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2nmpd_
  • Heterogens: PLP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2nmpA (A:)
smqekdassqgflphfqhfatqaihvgqdpeqwtsravvppislsttfkqgapgqhsgfe
ysrsgnptrnclekavaaldgakyclafasglaatvtithllkagdqiicmddvyggtnr
yfrqvasefglkisfvdcskiklleaaitpetklvwietptnptqkvidiegcahivhkh
gdiilvvdntfmspyfqrplalgadismysatkymnghsdvvmglvsvnceslhnrlrfl
qnslgavpspidcylcnrglktlhvrmekhfkngmavaqflesnpwvekviypglpshpq
helvkrqctgctgmvtfyikgtlqhaeiflknlklftlaeslggfeslaelpaimthasv
lkndrdvlgisdtlirlsvgledeedlledldqalkaahppsg

    Sequence, based on observed residues (ATOM records): (download) 
    >2nmpA (A:)
gflphfqhfatqaihvgqdpeqwtsravvppislsttfkqgnptrnclekavaaldgaky
clafasglaatvtithllkagdqiicmddvyggtnryfrqvasefglkisfvdcskikll
eaaitpetklvwietptnptqkvidiegcahivhkhgdiilvvdntfmspyfqrplalga
dismysatkymnghsdvvmglvsvnceslhnrlrflqnslgavpspidcylcnrglktlh
vrmekhfkngmavaqflesnpwvekviypglpshpqhelvkrqctgctgmvtfyikgtlq
haeiflknlklftlaeslggfeslaelpaimthasvlkndrdvlgisdtlirlsvglede
edlledldqalkaahp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2nmpB (B:)
smqekdassqgflphfqhfatqaihvgqdpeqwtsravvppislsttfkqgapgqhsgfe
ysrsgnptrnclekavaaldgakyclafasglaatvtithllkagdqiicmddvyggtnr
yfrqvasefglkisfvdcskiklleaaitpetklvwietptnptqkvidiegcahivhkh
gdiilvvdntfmspyfqrplalgadismysatkymnghsdvvmglvsvnceslhnrlrfl
qnslgavpspidcylcnrglktlhvrmekhfkngmavaqflesnpwvekviypglpshpq
helvkrqctgctgmvtfyikgtlqhaeiflknlklftlaeslggfeslaelpaimthasv
lkndrdvlgisdtlirlsvgledeedlledldqalkaahppsg

    Sequence, based on observed residues (ATOM records): (download) 
    >2nmpB (B:)
gflphfqhfatqaihvgqdpeqwtsravvppislsttfkqgapgqhsgfeysrsgnptrn
clekavaaldgakyclafasglaatvtithllkagdqiicmddvyggtnryfrqvasefg
lkisfvdcskiklleaaitpetklvwietptnptqkvidiegcahivhkhgdiilvvdnt
fmspyfqrplalgadismysatkymnghsdvvmglvsvnceslhnrlrflqnslgavpsp
idcylcnrglktlhvrmekhfkngmavaqflesnpwvekviypglpshpqhelvkrqctg
ctgmvtfyikgtlqhaeiflknlklftlaeslggfeslaelpaiisdtlirlsvgledee
dlledldqalkaahpp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2nmpC (C:)
smqekdassqgflphfqhfatqaihvgqdpeqwtsravvppislsttfkqgapgqhsgfe
ysrsgnptrnclekavaaldgakyclafasglaatvtithllkagdqiicmddvyggtnr
yfrqvasefglkisfvdcskiklleaaitpetklvwietptnptqkvidiegcahivhkh
gdiilvvdntfmspyfqrplalgadismysatkymnghsdvvmglvsvnceslhnrlrfl
qnslgavpspidcylcnrglktlhvrmekhfkngmavaqflesnpwvekviypglpshpq
helvkrqctgctgmvtfyikgtlqhaeiflknlklftlaeslggfeslaelpaimthasv
lkndrdvlgisdtlirlsvgledeedlledldqalkaahppsg

    Sequence, based on observed residues (ATOM records): (download) 
    >2nmpC (C:)
gflphfqhfatqaihvgqdpeqwtsravvppislsttfkqgapgqgfeysrsgnptrncl
ekavaaldgakyclafasglaatvtithllkagdqiicmddvyggtnryfrqvasefglk
isfvdcskiklleaaitpetklvwietptnptqkvidiegcahivhkhgdiilvvdntfm
spyfqrplalgadismysatkymnghsdvvmglvsvnceslhnrlrflqnslgavpspid
cylcnrglktlhvrmekhfkngmavaqflesnpwvekviypglpshpqhelvkrqctgct
gmvtfyikgtlqhaeiflknlklftlaeslggfeslaelpaimthasvlkndrdvlgisd
tlirlsvgledeedlledldqalkaahpps

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2nmpD (D:)
smqekdassqgflphfqhfatqaihvgqdpeqwtsravvppislsttfkqgapgqhsgfe
ysrsgnptrnclekavaaldgakyclafasglaatvtithllkagdqiicmddvyggtnr
yfrqvasefglkisfvdcskiklleaaitpetklvwietptnptqkvidiegcahivhkh
gdiilvvdntfmspyfqrplalgadismysatkymnghsdvvmglvsvnceslhnrlrfl
qnslgavpspidcylcnrglktlhvrmekhfkngmavaqflesnpwvekviypglpshpq
helvkrqctgctgmvtfyikgtlqhaeiflknlklftlaeslggfeslaelpaimthasv
lkndrdvlgisdtlirlsvgledeedlledldqalkaahppsg

    Sequence, based on observed residues (ATOM records): (download) 
    >2nmpD (D:)
gflphfqhfatqaihvgqdpeqwtsravvppislsttfkqgapgqhsgfeysrsgnptrn
clekavaaldgakyclafasglaatvtithllkagdqiicmddvyggtnryfrqvasefg
lkisfvdcskiklleaaitpetklvwietptnptqkvidiegcahivhkhgdiilvvdnt
fmspyfqrplalgadismysatkymnghsdvvmglvsvnceslhnrlrflqnslgavpsp
idcylcnrglktlhvrmekhfkngmavaqflesnpwvekviypglpshpqhelvkrqctg
ctgmvtfyikgtlqhaeiflknlklftlaeslggfeslaelpaimthaskndrdvlgisd
tlirlsvgledeedlledldqalkaahpps