PDB entry 2msr

View 2msr on RCSB PDB site
Description: Solution structure of LEDGF/p75 IBD in complex with MLL1 peptide (140-160)
Class: protein binding
Keywords: LEDGF/p75, MLL, Mixed Lineage Leukemia, PROTEIN BINDING
Deposited on 2014-08-05, released 2014-08-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-10-08, with a file datestamp of 2014-10-03.
Experiment type: NMR
Resolution: N/A
R-factor: N/A
AEROSPACI score: 0.06 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone-lysine N-methyltransferase 2A
    Species: Homo sapiens [TaxId:9606]
    Gene: KMT2A, ALL1, CXXC7, HRX, HTRX, MLL, MLL1, TRX1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: PC4 and SFRS1-interacting protein
    Species: Homo sapiens [TaxId:9606]
    Gene: PSIP1, DFS70, LEDGF, PSIP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot O75475 (5-87)
      • expression tag (0-4)
    Domains in SCOPe 2.08: d2msrb1, d2msrb2

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2msrB (B:)
snaasretsmdsrlqrihaeiknslkidnldvnrciealdelaslqvtmqqaqkhtemit
tlkkirrfkvsqvimekstmlynkfknm