PDB entry 2ktb

View 2ktb on RCSB PDB site
Description: Solution Structure of the Second Bromodomain of Human Polybromo in complex with an acetylated peptide from Histone 3
Class: protein binding
Keywords: bromodomain, Alternative splicing, Chromatin regulator, DNA-binding, Nucleus, Phosphoprotein, Transcription, Transcription regulation, PROTEIN BINDING
Deposited on 2010-01-26, released 2010-05-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-05-19, with a file datestamp of 2010-05-14.
Experiment type: NMR
Resolution: N/A
R-factor: N/A
AEROSPACI score: 0.02 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: H3_Peptide
    Database cross-references and differences (RAF-indexed):
    • PDB 2KTB (0-19)
  • Chain 'B':
    Compound: Protein polybromo-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PB1, PBRM1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q86U86 (1-120)
      • expression tag (0)
    Domains in SCOPe 2.08: d2ktbb1, d2ktbb2

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2ktbB (B:)
    stegsspaylkeileqlleaivvatnpsgrliselfqklpskvqypdyyaiikepidlkt
    iaqriqngsyksihamakdidllaknaktynepgsqvfkdansikkifymkkaeiehhem
    a