PDB entry 2k2g
View 2k2g on RCSB PDB site
Description: Solution structure of the wild-type catalytic domain of human matrix metalloproteinase 12 (MMP-12) in complex with a tight-binding inhibitor
Class: hydrolase
Keywords: macrophage elastase, matrix metalloproteinase, protein-ligand structure, catalytic domain, human gene, Calcium, Extracellular matrix, Glycoprotein, Hydrolase, Metal-binding, Metalloprotease, Polymorphism, Protease, Secreted, Zinc, Zymogen
Deposited on
2008-04-01, released
2008-05-20
The last revision prior to the SCOPe 2.04 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: NMR
Resolution: N/A
R-factor: N/A
AEROSPACI score: 0.02
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Macrophage metalloelastase
Species: HOMO SAPIENS
Gene: MMP12, HME
Database cross-references and differences (RAF-indexed):
- Uniprot P39900 (1-164)
- initiating methionine (0)
Domains in SCOPe 2.04: d2k2ga_ - Heterogens: ZN, DSV