PDB entry 2jix
View 2jix on RCSB PDB site
Description: crystal structure of abt-007 fab fragment with the soluble domain of epo receptor
Class: receptor/immune system
Keywords: immune system, receptor, transmembrane, receptor soluble domain, antibody, receptor-immune system complex
Deposited on
2007-07-02, released
2007-07-10
The last revision prior to the SCOPe 2.02 freeze date was dated
2010-08-11, with a file datestamp of
2010-08-06.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: 0.26
AEROSPACI score: 0.12
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: abt-007 fab fragment
Species: Escherichia coli [TaxId:562]
Database cross-references and differences (RAF-indexed):
- Chain 'B':
Compound: erythropoietin receptor
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d2jixb1, d2jixb2 - Chain 'C':
Compound: erythropoietin receptor
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d2jixc1, d2jixc2 - Chain 'D':
Compound: abt-007 fab fragment
Species: Escherichia coli [TaxId:562]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d2jixd1, d2jixd2 - Chain 'E':
Compound: erythropoietin receptor
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d2jixe1, d2jixe2 - Chain 'F':
Compound: abt-007 fab fragment
Species: Escherichia coli [TaxId:562]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d2jixf1, d2jixf2 - Chain 'G':
Compound: abt-007 fab fragment
Species: Escherichia coli [TaxId:562]
Database cross-references and differences (RAF-indexed):
- Chain 'H':
Compound: abt-007 fab fragment
Species: Escherichia coli [TaxId:562]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d2jixh1, d2jixh2 - Chain 'L':
Compound: abt-007 fab fragment
Species: Escherichia coli [TaxId:562]
Database cross-references and differences (RAF-indexed):
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2jixB (B:)
apppnlpdpkfeskaallaargpeellcfterledlvcfweeaasagvgpgnysfsyqle
depwklcrlhqaptargavrfwcslptadtssfvplelrvtaasgapryhrvihinevvl
ldapvglvarladesghvvlrwlpppetpmtshiryevdvsagngagsvqrveilegrte
cvlsnlrgrtrytfavrarmaepsfggfwsawsepvslltpsdld
Sequence, based on observed residues (ATOM records): (download)
>2jixB (B:)
dpkfeskaallaargpeellcfterledlvcfweeaasagvgpgnysfsyqledepwklc
rlhqaptargavrfwcslptadtssfvplelrvtaasgapryhrvihinevvlldapvgl
varladesghvvlrwlpppetpmtshiryevdvsagngagsvqrveilegrtecvlsnlr
grtrytfavrarmaepsfggfwsawsepvslltpsdl
- Chain 'C':
Sequence, based on SEQRES records: (download)
>2jixC (C:)
apppnlpdpkfeskaallaargpeellcfterledlvcfweeaasagvgpgnysfsyqle
depwklcrlhqaptargavrfwcslptadtssfvplelrvtaasgapryhrvihinevvl
ldapvglvarladesghvvlrwlpppetpmtshiryevdvsagngagsvqrveilegrte
cvlsnlrgrtrytfavrarmaepsfggfwsawsepvslltpsdld
Sequence, based on observed residues (ATOM records): (download)
>2jixC (C:)
kfeskaallaargpeellcfterledlvcfweeaasagvgpgnysfsyqledepwklcrl
hqaptargavrfwcslptadtssfvplelrvtaasgapryhrvihinevvlldapvglva
rladesghvvlrwlpppetpmtshiryevdvsagngagsvqrveilegrtecvlsnlrgr
trytfavrarmaepsfggfwsawsepvslltpsdl
- Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)
>2jixD (D:)
qvqlqesgpglvkpsetlsltctvsgasissyywswirqppgkglewigyiggegstnyn
pslksrvtisvdtsknqfslklrsvtaadtavyycarerlgigdywgqgtlvtvssastk
gpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglys
lssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk
- Chain 'E':
Sequence, based on SEQRES records: (download)
>2jixE (E:)
apppnlpdpkfeskaallaargpeellcfterledlvcfweeaasagvgpgnysfsyqle
depwklcrlhqaptargavrfwcslptadtssfvplelrvtaasgapryhrvihinevvl
ldapvglvarladesghvvlrwlpppetpmtshiryevdvsagngagsvqrveilegrte
cvlsnlrgrtrytfavrarmaepsfggfwsawsepvslltpsdld
Sequence, based on observed residues (ATOM records): (download)
>2jixE (E:)
dpkfeskaallaargpeellcfterledlvcfweeaasagvgpgnysfsyqledepwklc
rlhqaptargavrfwcslptadtssfvplelrvtaasgapryhrvihinevvlldapvgl
varladesghvvlrwlpppetpmtshiryevdvsagngagsvqrveilegrtecvlsnlr
grtrytfavrarmaepsfggfwsawsepvslltpsdl
- Chain 'F':
Sequence; same for both SEQRES and ATOM records: (download)
>2jixF (F:)
qvqlqesgpglvkpsetlsltctvsgasissyywswirqppgkglewigyiggegstnyn
pslksrvtisvdtsknqfslklrsvtaadtavyycarerlgigdywgqgtlvtvssastk
gpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglys
lssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk
- Chain 'G':
No sequence available.
- Chain 'H':
Sequence; same for both SEQRES and ATOM records: (download)
>2jixH (H:)
qvqlqesgpglvkpsetlsltctvsgasissyywswirqppgkglewigyiggegstnyn
pslksrvtisvdtsknqfslklrsvtaadtavyycarerlgigdywgqgtlvtvssastk
gpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglys
lssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk
- Chain 'L':
No sequence available.