PDB entry 2jff
View 2jff on RCSB PDB site
Description: Crystal structure of MurD ligase in complex with D-Glu containing sulfonamide inhibitor
Class: ligase
Keywords: murd-inhibitor complex, peptidoglycan synthesis, ligase, cell wall, cell shape, cell cycle, nucleotide-binding, sulfonamide inhibitor, murd ligase, ATP-binding, cell division
Deposited on
2007-02-01, released
2007-05-15
The last revision prior to the SCOPe 2.08 freeze date was dated
2018-01-31, with a file datestamp of
2018-01-26.
Experiment type: XRAY
Resolution: 1.89 Å
R-factor: N/A
AEROSPACI score: 0.34
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: udp-n-acetylmuramoylalanine--d-glutamate ligase
Species: Escherichia coli [TaxId:562]
Database cross-references and differences (RAF-indexed):
- PDB 2JFF (438-End)
- Uniprot P14900 (1-437)
Domains in SCOPe 2.08: d2jffa1, d2jffa2, d2jffa3, d2jffa4 - Heterogens: LK2, SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2jffA (A:)
madyqgknvviiglgltglscvdfflargvtprvmdtrmtppgldklpeaverhtgslnd
ewlmaadlivaspgialahpslsaaadagieivgdielfcreaqapivaitgsngkstvt
tlvgemakaagvnvgvggniglpalmllddecelyvlelssfqlettsslqavaatilnv
tedhmdrypfglqqyraaklriyenakvcvvnaddaltmpirgadercvsfgvnmgdyhl
nhqqgetwlrvkgekvlnvkemklsgqhnytnalaalaladaaglprasslkalttftgl
phrfevvlehngvrwindskatnvgsteaalnglhvdgtlhlllggdgksadfsplaryl
ngdnvrlycfgrdgaqlaalrpevaeqtetmeqamrllaprvqpgdmvllspacasldqf
knfeqrgnefarlakelgshhhhhh
Sequence, based on observed residues (ATOM records): (download)
>2jffA (A:)
adyqgknvviiglgltglscvdfflargvtprvmdtrmtppgldklpeaverhtgslnde
wlmaadlivaspgialahpslsaaadagieivgdielfcreaqapivaitgsngkstvtt
lvgemakaagvnvgvggniglpalmllddecelyvlelssfqlettsslqavaatilnvt
edhmdrypfglqqyraaklriyenakvcvvnaddaltmpirrcvsfgvnmgdyhlnhqet
wlrvkgekvlnvkemklsgqhnytnalaalaladaaglprasslkalttftglphrfevv
lehngvrwindskatnvgsteaalnglhvdgtlhlllggdgksadfsplarylngdnvrl
ycfgrdgaqlaalrpevaeqtetmeqamrllaprvqpgdmvllspacasldqfknfeqrg
nefarlakelgsh