PDB entry 2jfa

View 2jfa on RCSB PDB site
Description: estrogen receptor alpha lbd in complex with an affinity-selected corepressor peptide
Class: transcription
Keywords: transcription, transcription factor, phage display, metal-binding, corepressor, lipid-binding, transcription regulation, ligand-binding domain (lbd), nuclear protein, phosphorylation, steroid- binding, receptor, zinc-finger, DNA-binding, nuclear receptor, peptide antagonist
Deposited on 2007-01-29, released 2007-02-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-24, with a file datestamp of 2018-01-19.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Estrogen receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2jfaa_
  • Chain 'B':
    Compound: Estrogen receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2jfab_
  • Chain 'P':
    Compound: corepressor peptide
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 2JFA (0-End)
  • Chain 'Q':
    Compound: corepressor peptide
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 2JFA (0-End)
  • Heterogens: RAL, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2jfaA (A:)
mgsshhhhhhssglvprgshmenslalsltadqmvsalldaeppilyseydptrpfseas
mmglltnladrelvhminwakrvpgfvdltlhdqvhllecawleilmiglvwrsmehpgk
llfapnllldrnqgkcvegmveifdmllatssrfrmmnlqgeefvclksiillnsgvytf
lsstlksleekdhihrvldkitdtlihlmakagltlqqqhqrlaqlllilshirhmsnkg
mehlysmkcknv

    Sequence, based on observed residues (ATOM records): (download) 
    >2jfaA (A:)
slalsltadqmvsalldaeppilyseypfseasmmglltnladrelvhminwakrvpgfv
dltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifdml
latssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtlih
lmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2jfaB (B:)
mgsshhhhhhssglvprgshmenslalsltadqmvsalldaeppilyseydptrpfseas
mmglltnladrelvhminwakrvpgfvdltlhdqvhllecawleilmiglvwrsmehpgk
llfapnllldrnqgkcvegmveifdmllatssrfrmmnlqgeefvclksiillnsgvytf
lsstlksleekdhihrvldkitdtlihlmakagltlqqqhqrlaqlllilshirhmsnkg
mehlysmkcknv

    Sequence, based on observed residues (ATOM records): (download) 
    >2jfaB (B:)
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdt
lihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysm

  • Chain 'P':
    No sequence available.

  • Chain 'Q':
    No sequence available.