PDB entry 2j9m

View 2j9m on RCSB PDB site
Description: crystal structure of cdk2 in complex with macrocyclic aminopyrimidine
Class: transferase
Keywords: serine-threonine protein kinase, serine/threonine-protein kinase, nucleotide-binding, arylamine n-acetyltransferase, cell division, drug metabolism, phosphorylation, ATP-binding, transferase, mycobacteria, polymorphism, nat, kinase, mitosis, isoniazid, cell cycle
Deposited on 2006-11-13, released 2007-11-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.219
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2j9ma_
  • Heterogens: PY8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2j9mA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >2j9mA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirpstaireisllkelnhpnivklld
    vihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdl
    kpqnllintegaikladfglvtlwyrapeillgckyystavdiwslgcifaemvtrralf
    pgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrsll
    sqmlhydpnkrisakaalahpffqdvtkpvphlrl