PDB entry 2j88

View 2j88 on RCSB PDB site
Description: hyaluronidase in complex with a monoclonal igg fab fragment
Class: hydrolase
Keywords: glycoprotein, glycosidase family 56, zymogen, allergen, 7-stranded (beta/alpha) tim barrel, hydrolase, glycosidase, immunoglobulin domain
Deposited on 2006-10-23, released 2007-04-03
The last revision prior to the SCOP 1.73 freeze date was dated 2007-04-03, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.212
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hyalurononglucosaminidase
    Species: APIS MELLIFERA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2j88a1
  • Chain 'H':
    Compound: fab
    Database cross-references and differences (RAF-indexed):
    • PDB 2J88 (100-End)
    Domains in SCOP 1.73: d2j88h1
  • Chain 'L':
    Compound: fab
    Domains in SCOP 1.73: d2j88l1, d2j88l2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2j88A (A:)
    tpdnnktvrefnvywnvptfmchkyglrfeevsekygilqnwmdkfrgeeiailydpgmf
    pallkdpngnvvarnggvpqlgnltkhlqvfrdhlinqipdksfpgvgvidfeswrpifr
    qnwaslqpykklsvevvrrehpfwddqrveqeakrrfekygqlfmeetlkaakrmrpaan
    wgyyaypycynltpnqpsaqceattmqendkmswlfesedvllpsvylrwnltsgervgl
    vggrvkealriarqmttsrkkvlpyywykyqdrrdtdlsradleatlrkitdlgadgfii
    wgssddintkakclqfreylnnelgpavkrialnnnandrltvdvsvdqv
    

    Sequence, based on observed residues (ATOM records): (download)
    >2j88A (A:)
    efnvywnvptfmchkyglrfeevsekygilqnwmdkfrgeeiailydpgmfpallkvvar
    nggvpqlgnltkhlqvfrdhlinqipdksfpgvgvidfeswrpifrqnwaslqpykklsv
    evvrrehpfwddqrveqeakrrfekygqlfmeetlkaakrmrpaanwgyyaypycynltp
    nqpsaqceattmqendkmswlfesedvllpsvylrwnltsgervglvggrvkealriarq
    mttsrkkvlpyywykyqdrrdtdlsradleatlrkitdlgadgfiiwgssddintkakcl
    qfreylnnelgpavkrial
    

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >2j88H (H:)
    qvtlkesgpgilqpsqtlsltcsfsgfslstsgmgvswirqpsgkglewlahiywdddkr
    ynpslksrltiskdtsrnqvflkitsvdtadtatyyctlyygsvdywgqgtsvtvssakt
    tppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlyt
    lsssvtvpsst
    

    Sequence, based on observed residues (ATOM records): (download)
    >2j88H (H:)
    vtlkesgpgilqpsqtlsltcsfsgfslstsgmgvswirqpsgkglewlahiywdddkry
    npslksrltiskdtsrnqvflkitsvdtadtatyyctlyygsvdywgqgtsvtvssaktt
    ppsvygclvkgyfpepvtvtwnsghtfpavlqsdlytlsssv
    

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >2j88L (L:)
    diqmtqspaslsasvgetvtitcraseniysyltwyqqkqgkspqllvynaktlaegvps
    rfsgsgsgtqfslkisslqpedfgnyycqhhygtrtfgggtrleikradaaptvsifpps
    seqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstltl
    tkdeyerhnsytceathktstspivksfnrnec
    

    Sequence, based on observed residues (ATOM records): (download)
    >2j88L (L:)
    diqmtqspaslsasvgetvtitcraseniysyltwyqqkqgkspqllvynaktlaegvps
    rfsgsgsgtqfslkisslqpedfgnyycqhhygtrtfgggtrleikradaaptvsifvvc
    flnnfypkdinvkwkgvlnswtdqddstysmsstltltkdeytceathktstspi