PDB entry 2j7q

View 2j7q on RCSB PDB site
Description: crystal structure of the ubiquitin-specific protease encoded by murine cytomegalovirus tegument protein m48 in complex with a ubquitin-based suicide substrate
Class: hydrolase
Keywords: herpesviridae, nuclear protein, covalent enzyme-ligand complex, deubiquitinating enzyme, hydrolase, papain-like fold, cysteine protease
Deposited on 2006-10-16, released 2007-03-20
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.157
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: mcmv tegument protein m48 encoded ubiquitin- specific protease, m48usp
    Species: MURINE CYTOMEGALOVIRUS [TaxId:10366]
    Database cross-references and differences (RAF-indexed):
    • PDB 2J7Q (0-231)
    Domains in SCOPe 2.06: d2j7qa1
  • Chain 'B':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2j7qb_
  • Chain 'C':
    Compound: mcmv tegument protein m48 encoded ubiquitin- specific protease, m48usp
    Species: MURINE CYTOMEGALOVIRUS [TaxId:10366]
    Database cross-references and differences (RAF-indexed):
    • PDB 2J7Q (0-231)
    Domains in SCOPe 2.06: d2j7qc1
  • Chain 'D':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2j7qd_
  • Heterogens: MG, GVE, PG4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2j7qA (A:)
    mkivrasrdqsapvygpragsqcmsncftflhtcylmgidpvldttsldavldsgarlda
    iadekvkrqaltdhpyrlgteiptvietpagitghalsrpfngtaetqdlggykclgild
    fltyargkplpvyiivtvgvhtrgvivargatyvfdphttdlsaeaavyvcddfteaisa
    lsfftemigdfyydavlvyftrcrttlispsellvqimdqykdpdidasvms
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2j7qB (B:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrg
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2j7qC (C:)
    mkivrasrdqsapvygpragsqcmsncftflhtcylmgidpvldttsldavldsgarlda
    iadekvkrqaltdhpyrlgteiptvietpagitghalsrpfngtaetqdlggykclgild
    fltyargkplpvyiivtvgvftrgvivargatyvfdphttdlsaeaavyvcddfteaisa
    lsfftemigdfyydavlvyftrcrttlispsellvqimdqykdpdidasvms
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2j7qD (D:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrg