PDB entry 2j3z

View 2j3z on RCSB PDB site
Description: crystal structure of the enzymatic component c2-I of the c2-toxin from clostridium botulinum at ph 6.1
Class: toxin
Keywords: ADP-ribosyltransferase, toxin, clostridium botulinum
Deposited on 2006-08-23, released 2006-10-11
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.201
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: c2 toxin component I
    Species: Clostridium botulinum [TaxId:1491]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O69275 (Start-430)
      • engineered mutation (76)
      • conflict (120)
    Domains in SCOPe 2.06: d2j3za1, d2j3za2
  • Chain 'B':
    Compound: c2 toxin component I
    Species: Clostridium botulinum [TaxId:1491]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O69275 (Start-430)
      • engineered mutation (76)
      • conflict (120)
    Domains in SCOPe 2.06: d2j3zb1, d2j3zb2
  • Chain 'C':
    Compound: c2 toxin component I
    Species: Clostridium botulinum [TaxId:1491]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O69275
      • engineered mutation (76)
      • conflict (120)
    Domains in SCOPe 2.06: d2j3zc1, d2j3zc2
  • Chain 'D':
    Compound: c2 toxin component I
    Species: Clostridium botulinum [TaxId:1491]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O69275
      • engineered mutation (76)
      • conflict (120)
    Domains in SCOPe 2.06: d2j3zd1, d2j3zd2
  • Chain 'E':
    Compound: c2 toxin component I
    Species: Clostridium botulinum [TaxId:1491]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O69275
      • engineered mutation (76)
      • conflict (120)
    Domains in SCOPe 2.06: d2j3ze1
  • Chain 'F':
    Compound: c2 toxin component I
    Species: Clostridium botulinum [TaxId:1491]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O69275
      • engineered mutation (76)
      • conflict (120)
    Domains in SCOPe 2.06: d2j3zf1, d2j3zf2
  • Heterogens: CO, GOL, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2j3zA (A:)
mpiikepidfinkpeseakkwgkeeekrwftklnnleevavnqlknkeyktkidnfstdi
lfssltaieimkedenrnlfdverireallkntldrdaigyvnftpkelginfsirdvel
drdisdetldkvrqqiinqeytkfsfislglndnsinesvpvivktrvpttfdygvlndk
etvslllnqgfsiipesaiittikgkdyiliegslsqeldfynkgseawgaenygdyisk
lsheqlgalegylhsdykainsylrnnrvpnndelnkkielissalsvkpipqtliayrr
vdgipfdlpsdfsfdkkengeiiadkqklnefidkwtgkeienlsfsstslkstpssfsk
srfifrlrlsegaigafiygfsgfqdeqeillnknstfkifritpitsiinrvtkmtqvv
idaegiqnkei

    Sequence, based on observed residues (ATOM records): (download) 
    >2j3zA (A:)
piikepidfinkpeseakkwgkeeekrwftklnnleevavnqlknkeyktkidnfstdil
fssltaieimkedenrnlfdverireallkntldrdaigyvnftpkelginfsirdveld
rdisdetldkvrqqiinqeytkfsfislglndnsinesvpvivktrvpttfdygvlndke
tvslllnqgfsiipesaiittikgkdyiliegslsqeldfynkgseawgaenygdyiskl
sheqlgalegylhsdykainsylrnnrvpnndelnkkielissalsvkpipqtliayrrv
dgipfdlpsdfsfdkkengeiiadkqklnefidkwtgkeienlsfsstslkstpssfsks
rfifrlrlsegaigafiygfsgfqdeqeillnknstfkifritpitsiinrvtkmtqvvi
daegiqnkei

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2j3zB (B:)
mpiikepidfinkpeseakkwgkeeekrwftklnnleevavnqlknkeyktkidnfstdi
lfssltaieimkedenrnlfdverireallkntldrdaigyvnftpkelginfsirdvel
drdisdetldkvrqqiinqeytkfsfislglndnsinesvpvivktrvpttfdygvlndk
etvslllnqgfsiipesaiittikgkdyiliegslsqeldfynkgseawgaenygdyisk
lsheqlgalegylhsdykainsylrnnrvpnndelnkkielissalsvkpipqtliayrr
vdgipfdlpsdfsfdkkengeiiadkqklnefidkwtgkeienlsfsstslkstpssfsk
srfifrlrlsegaigafiygfsgfqdeqeillnknstfkifritpitsiinrvtkmtqvv
idaegiqnkei

    Sequence, based on observed residues (ATOM records): (download) 
    >2j3zB (B:)
piikepidfinkpeseakkwgkeeekrwftklnnleevavnqlknkeyktkidnfstdil
fssltaieimkedenrnlfdverireallkntldrdaigyvnftpkelginfsirdveld
rdisdetldkvrqqiinqeytkfsfislglndnsinesvpvivktrvpttfdygvlndke
tvslllnqgfsiipesaiittikgkdyiliegslsqeldfynkgseawgaenygdyiskl
sheqlgalegylhsdykainsylrnnrvpnndelnkkielissalsvkpipqtliayrrv
dgipfdlpsdfsfdkkengeiiadkqklnefidkwtgkeienlsfsstslkstpssfsks
rfifrlrlsegaigafiygfsgfqdeqeillnknstfkifritpitsiinrvtkmtqvvi
daegiqnkei

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2j3zC (C:)
mpiikepidfinkpeseakkwgkeeekrwftklnnleevavnqlknkeyktkidnfstdi
lfssltaieimkedenrnlfdverireallkntldrdaigyvnftpkelginfsirdvel
drdisdetldkvrqqiinqeytkfsfislglndnsinesvpvivktrvpttfdygvlndk
etvslllnqgfsiipesaiittikgkdyiliegslsqeldfynkgseawgaenygdyisk
lsheqlgalegylhsdykainsylrnnrvpnndelnkkielissalsvkpipqtliayrr
vdgipfdlpsdfsfdkkengeiiadkqklnefidkwtgkeienlsfsstslkstpssfsk
srfifrlrlsegaigafiygfsgfqdeqeillnknstfkifritpitsiinrvtkmtqvv
idaegiqnkei

    Sequence, based on observed residues (ATOM records): (download) 
    >2j3zC (C:)
piikepidfinkpeseakkwgkeeekrwftklnnleevavnqlknkeyktkidnfstdil
fssltaieimkedenrnlfdverireallkntldrdaigyvnftpkelginfsirdveld
rdisdetldkvrqqiinqeytkfsfislglndnsinesvpvivktrvpttfdygvlndke
tvslllnqgfsiipesaiittikgkdyiliegslsqeldfynkgseawgaenygdyiskl
sheqlgalegylhsdykainsylrnnrvpnndelnkkielissalsvkpipqtliayrrv
dgipfdlpsdfsfdkkengeiiadkqklnefidkwtgkeienlsfsstslkstpssfsks
rfifrlrlsegaigafiygfsgfqdeqeillnknstfkifritpitsiinrvtkmtqvvi
daegiqnk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2j3zD (D:)
mpiikepidfinkpeseakkwgkeeekrwftklnnleevavnqlknkeyktkidnfstdi
lfssltaieimkedenrnlfdverireallkntldrdaigyvnftpkelginfsirdvel
drdisdetldkvrqqiinqeytkfsfislglndnsinesvpvivktrvpttfdygvlndk
etvslllnqgfsiipesaiittikgkdyiliegslsqeldfynkgseawgaenygdyisk
lsheqlgalegylhsdykainsylrnnrvpnndelnkkielissalsvkpipqtliayrr
vdgipfdlpsdfsfdkkengeiiadkqklnefidkwtgkeienlsfsstslkstpssfsk
srfifrlrlsegaigafiygfsgfqdeqeillnknstfkifritpitsiinrvtkmtqvv
idaegiqnkei

    Sequence, based on observed residues (ATOM records): (download) 
    >2j3zD (D:)
epidfinkpeseakkwgkeeekrwftklnnleevavnqlknkeyktkidnfstdilfssl
taieimkedenrnlfdverireallkntldrdaigyvnftpkelginfsirdveldrdis
detldkvrqqiinqeytkfsfislglndnsinesvpvivktrvpttfdygvlndketvsl
llnqgfsiipesaiittikgkdyiliegslsqeldfynkgseawgaenygdyisklsheq
lgalegylhsdykainsylrnnrvpnndelnkkielissalsvkpipqtliayrrvdgip
fdlpsdfsfdkkengeiiadkqklnefidkwtgkeienlsfsstslkstpssfsksrfif
rlrlsegaigafiygfsgfqdeqeillnknstfkifritpitsiinrvtkmtqvvidaeg
i

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2j3zE (E:)
mpiikepidfinkpeseakkwgkeeekrwftklnnleevavnqlknkeyktkidnfstdi
lfssltaieimkedenrnlfdverireallkntldrdaigyvnftpkelginfsirdvel
drdisdetldkvrqqiinqeytkfsfislglndnsinesvpvivktrvpttfdygvlndk
etvslllnqgfsiipesaiittikgkdyiliegslsqeldfynkgseawgaenygdyisk
lsheqlgalegylhsdykainsylrnnrvpnndelnkkielissalsvkpipqtliayrr
vdgipfdlpsdfsfdkkengeiiadkqklnefidkwtgkeienlsfsstslkstpssfsk
srfifrlrlsegaigafiygfsgfqdeqeillnknstfkifritpitsiinrvtkmtqvv
idaegiqnkei

    Sequence, based on observed residues (ATOM records): (download) 
    >2j3zE (E:)
epidfinkpeseakkwgkeeekrwftklnnleevavnqlknkeyktkidnfstdilfssl
taieimkedenrnlfdverireallkntldrdaigyvnftpkelginfsirdveldrdis
detldkvrqqiinqeytkfsfislglndnsinesvpvivktrvpttfdygvlndketvsl
llnqgfsiipesaiittikgkdyiliegslsqeldfynkgseawgaenygdyisklsheq
lgalegylhsdykainsylrnnrvpnndelnkkielissalsvkpipqtliayrrvdgip
fdlpsdfsfdkkengeiiadkqklnefidkwtgkeienlsfsstslkstpssfsksrfif
rlrlsegaigafiygfsgfqdeqeillnknstfkifritpitsiinrvtkmtqvvidaeg
iqn

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2j3zF (F:)
mpiikepidfinkpeseakkwgkeeekrwftklnnleevavnqlknkeyktkidnfstdi
lfssltaieimkedenrnlfdverireallkntldrdaigyvnftpkelginfsirdvel
drdisdetldkvrqqiinqeytkfsfislglndnsinesvpvivktrvpttfdygvlndk
etvslllnqgfsiipesaiittikgkdyiliegslsqeldfynkgseawgaenygdyisk
lsheqlgalegylhsdykainsylrnnrvpnndelnkkielissalsvkpipqtliayrr
vdgipfdlpsdfsfdkkengeiiadkqklnefidkwtgkeienlsfsstslkstpssfsk
srfifrlrlsegaigafiygfsgfqdeqeillnknstfkifritpitsiinrvtkmtqvv
idaegiqnkei

    Sequence, based on observed residues (ATOM records): (download) 
    >2j3zF (F:)
epidfinkpeseakkwgkeeekrwftklnnleevavnqlknkeyktkidnfstdilfssl
taieimkedenrnlfdverireallkntldrdaigyvnftpkelginfsirdveldrdis
detldkvrqqiinqeytkfsfislglndnsinesvpvivktrvpttfdygvlndketvsl
llnqgfsiipesaiittikgkdyiliegslsqeldfynkgseawgaenygdyisklsheq
lgalegylhsdykainsylrnnrvpnndelnkkielissalsvkpipqtliayrrvdgip
fdlpsdfsfdkkengeiiadkqklnefidkwtgkeienlsfsstslkstpssfsksrfif
rlrlsegaigafiygfsgfqdeqeillnknstfkifritpitsiinrvtkmtqvvidaeg
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