PDB entry 2j14

View 2j14 on RCSB PDB site
Description: 3,4,5-trisubstituted isoxazoles as novel ppardelta agonists: part2
Class: transcription
Keywords: nuclear receptor fold, transcription regulation, ppar, zinc, receptor, activator, fatty acids, nuclear protein, alternative splicing, zinc-finger, DNA-binding, transcription, metal-binding
Deposited on 2006-08-08, released 2006-09-06
The last revision prior to the SCOP 1.73 freeze date was dated 2006-09-27, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.224
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peroxisome proliferator-activated receptor delta
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2j14a1
  • Chain 'B':
    Compound: Peroxisome proliferator-activated receptor delta
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2j14b1
  • Heterogens: GNI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2j14A (A:)
mghhhhhhgsqynpqvadlkafskhiynaylknfnmtkkkarsiltgkashtapfvihdi
etlwqaekglvwkqlvnglppykeisvhvfyrcqcttvetvreltefaksipsfsslfln
dqvtllkygvheaifamlasivnkdgllvangsgfvtreflrslrkpfsdiiepkfefav
kfnalelddsdlalfiaaiilcgdrpglmnvprveaiqdtilralefhlqanhpdaqylf
pkllqkmadlrqlvtehaqmmqrikktetetslhpllqeiykdmy

    Sequence, based on observed residues (ATOM records): (download) 
    >2j14A (A:)
dlkafskhiynaylknfnmtkkkarsiltshtapfvihdietlwqaeklppykeisvhvf
yrcqcttvetvreltefaksipsfsslflndqvtllkygvheaifamlasivnkdgllva
ngsgfvtreflrslrkpfsdiiepkfefavkfnalelddsdlalfiaaiilcgdrpglmn
vprveaiqdtilralefhlqanhpdaqylfpkllqkmadlrqlvtehaqmmqrikktete
tslhpllqeiykdm

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2j14B (B:)
mghhhhhhgsqynpqvadlkafskhiynaylknfnmtkkkarsiltgkashtapfvihdi
etlwqaekglvwkqlvnglppykeisvhvfyrcqcttvetvreltefaksipsfsslfln
dqvtllkygvheaifamlasivnkdgllvangsgfvtreflrslrkpfsdiiepkfefav
kfnalelddsdlalfiaaiilcgdrpglmnvprveaiqdtilralefhlqanhpdaqylf
pkllqkmadlrqlvtehaqmmqrikktetetslhpllqeiykdmy

    Sequence, based on observed residues (ATOM records): (download) 
    >2j14B (B:)
lkafskhiynaylknfnmtkkkarsiltgkpfvihdietlwqaekgllppykeisvhvfy
rcqcttvetvreltefaksipsfsslflndqvtllkygvheaifamlasivnkdgllvan
gsgfvtreflrslrkpfsdiiepkfefavkfnalelddsdlalfiaaiilcgdrpglmnv
prveaiqdtilralefhlqanhpdaqylfpkllqkmadlrqlvtehaqmmqrikktetet
slhpllqeiykd