PDB entry 2iwc

View 2iwc on RCSB PDB site
Description: Benzylpenicilloyl-acylated MecR1 extracellular antibiotic-sensor domain.
Class: antibiotic resistance
Keywords: bacterial antibiotic resistance, mrsa, beta-lactamase, benzylpenicillin, antibiotic resistance, methicillin resistance, beta-lactamic antibiotics, penicillin-binding protein
Deposited on 2006-06-27, released 2006-07-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-10-24, with a file datestamp of 2018-10-19.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: methicillin resistance mecr1 protein
    Species: Staphylococcus aureus subsp. aureus N315 [TaxId:158879]
    Database cross-references and differences (RAF-indexed):
    • PDB 2IWC (0-2)
    • Uniprot P0A0B0 (3-254)
    Domains in SCOPe 2.08: d2iwca_
  • Heterogens: PNM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2iwcA (A:)
    ghmsahvqqdkyetnvsykklnqlapyfkgfdgsfvlynereqaysiynepeskqryspn
    stykiylalmafdqnllslnhteqqwdkhqypfkewnqdqnlnssmkysvnwyyenlnkh
    lrqdevksyldlieygneeisgnenywnesslkisaieqvnllknmkqhnmhfdnkaiek
    vensmtlkqkdtykyvgktgtgivnhkeangwfvgyvetkdntyyfathlkgednangek
    aqqiserilkemeli