PDB entry 2io3

View 2io3 on RCSB PDB site
Description: Crystal structure of human Senp2 in complex with RanGAP1-SUMO-2
Class: protein binding, hydrolase
Keywords: SUMO, Ubiquitin, Senp, Ulp, complex, PROTEIN BINDING, HYDROLASE
Deposited on 2006-10-09, released 2006-11-14
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: 0.277
AEROSPACI score: 0.08 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Sentrin-specific protease 2
    Species: Homo sapiens [TaxId:9606]
    Gene: SENP2, KIAA1331
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HC62 (Start-231)
      • engineered (190)
    Domains in SCOPe 2.06: d2io3a1
  • Chain 'B':
    Compound: Small ubiquitin-related modifier 2
    Species: Homo sapiens [TaxId:9606]
    Gene: SUMO2, SMT3B, SMT3H2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2io3b1
  • Chain 'C':
    Compound: ran gtpase-activating protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: RANGAP1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P46060 (Start-171)
      • engineered (157)
    Domains in SCOPe 2.06: d2io3c1

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2io3A (A:)
    gshmasdlleltedmekeisnalghgpqdeilssafklritrgdiqtlknyhwlndevin
    fymnllvernkkqgypalhvfstffypklksggyqavkrwtkgvnlfeqeiilvpihrkv
    hwslvvidlrkkclkyldsmgqkghriceillqylqdesktkrnsdlnllewthhsmkph
    eipqqlngsdsgmftckyadyisrdkpitftqhqmplfrkkmvweilhqqll
    

    Sequence, based on observed residues (ATOM records): (download)
    >2io3A (A:)
    leltedmekeisnalghgpqdeilssafklritrgdiqtlknyhwlndevinfymnllve
    rnkkqgypalhvfstffypklksggyqavkrwtkgvnlfeqeiilvpihrkvhwslvvid
    lrkkclkyldsmgqkghriceillqylqdesktkrnsdlnllewthhsmkpheipqqlng
    sdsgmftckyadyisrdkpitftqhqmplfrkkmvweilhqqll
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2io3B (B:)
    mandhinlkvagqdgsvvqfkikrhtplsklmkaycerqglsmrqirfrfdgqpinetdt
    paqlemededtidvfqqqtgg
    

    Sequence, based on observed residues (ATOM records): (download)
    >2io3B (B:)
    lkvagqdgsvvqfkikrhtplsklmkaycerqglsmrqirfrfdgqpinetdtpaqleme
    dedtidvfqqqtgg
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2io3C (C:)
    slntgepapvlsspppadvstflafpspekllrlgpkssvliaqqtdtsdpekvvsaflk
    vssvfkdeatvrmavqdavdalmqkafnsssfnsntfltrllvhmgllksedkvkaianl
    ygplmalnhmvqqdyfpkalaplllafvtkpnsalesssfarhsllqtlykv
    

    Sequence, based on observed residues (ATOM records): (download)
    >2io3C (C:)
    advstflafpspekllrlgpkssvliaqqtdtsdpekvvsaflkvssvfkdeatvrmavq
    davdalmqkafnsssfnsntfltrllvhmgllksedkvkaianlygplmalnhmvqqdyf
    pkalaplllafvtkpnsalesssfarhsllqtlykv