PDB entry 2io1

View 2io1 on RCSB PDB site
Description: Crystal structure of human Senp2 in complex with preSUMO-3
Class: protein binding, hydrolase
Keywords: SUMO, Ubiquitin, Senp, Ulp, complex, PROTEIN BINDING, HYDROLASE
Deposited on 2006-10-09, released 2006-11-14
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.204
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Sentrin-specific protease 2
    Species: Homo sapiens [TaxId:9606]
    Gene: SENP2, KIAA1331
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HC62 (Start-231)
      • engineered (190)
    Domains in SCOPe 2.05: d2io1a_
  • Chain 'B':
    Compound: Small ubiquitin-related modifier 3 precursor
    Species: Homo sapiens [TaxId:9606]
    Gene: SUMO3, SMT3A, SMT3H1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2io1b_
  • Chain 'C':
    Compound: Sentrin-specific protease 2
    Species: Homo sapiens [TaxId:9606]
    Gene: SENP2, KIAA1331
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HC62 (Start-231)
      • engineered (190)
    Domains in SCOPe 2.05: d2io1c_
  • Chain 'D':
    Compound: Small ubiquitin-related modifier 3 precursor
    Species: Homo sapiens [TaxId:9606]
    Gene: SUMO3, SMT3A, SMT3H1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2io1d_
  • Chain 'E':
    Compound: Sentrin-specific protease 2
    Species: Homo sapiens [TaxId:9606]
    Gene: SENP2, KIAA1331
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HC62 (Start-231)
      • engineered (190)
    Domains in SCOPe 2.05: d2io1e_
  • Chain 'F':
    Compound: Small ubiquitin-related modifier 3 precursor
    Species: Homo sapiens [TaxId:9606]
    Gene: SUMO3, SMT3A, SMT3H1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2io1f_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2io1A (A:)
gshmasdlleltedmekeisnalghgpqdeilssafklritrgdiqtlknyhwlndevin
fymnllvernkkqgypalhvfstffypklksggyqavkrwtkgvnlfeqeiilvpihrkv
hwslvvidlrkkclkyldsmgqkghriceillqylqdesktkrnsdlnllewthhsmkph
eipqqlngsdsgmftckyadyisrdkpitftqhqmplfrkkmvweilhqqll

    Sequence, based on observed residues (ATOM records): (download) 
    >2io1A (A:)
eltedmekeisnalghgpqdeilssafklritrgdiqtlknyhwlndevinfymnllver
nkkqgypalhvfstffypklksggyqavkrwtkgvnlfeqeiilvpihrkvhwslvvidl
rkkclkyldsmgqkghriceillqylqdesktkrnsdlnllewthhsmkpheipqqlngs
dsgmftckyadyisrdkpitftqhqmplfrkkmvweilhqqll

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2io1B (B:)
gshmndhinlkvagqdgsvvqfkikrhtplsklmkaycerqglsmrqirfrfdgqpinet
dtpaqlemededtidvfqqqtggvpesslaghsf

    Sequence, based on observed residues (ATOM records): (download) 
    >2io1B (B:)
dhinlkvagqdgsvvqfkikrhtplsklmkaycerqglsmrqirfrfdgqpinetdtpaq
lemededtidvfqqqtggvpe

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2io1C (C:)
gshmasdlleltedmekeisnalghgpqdeilssafklritrgdiqtlknyhwlndevin
fymnllvernkkqgypalhvfstffypklksggyqavkrwtkgvnlfeqeiilvpihrkv
hwslvvidlrkkclkyldsmgqkghriceillqylqdesktkrnsdlnllewthhsmkph
eipqqlngsdsgmftckyadyisrdkpitftqhqmplfrkkmvweilhqqll

    Sequence, based on observed residues (ATOM records): (download) 
    >2io1C (C:)
leltedmekeisnalghgpqdeilssafklritrgdiqtlknyhwlndevinfymnllve
rnkkqgypalhvfstffypklksggyqavkrwtkgvnlfeqeiilvpihrkvhwslvvid
lrkkclkyldsmgqkghriceillqylqdesktkrnsdlnllewthhsmkpheipqqlng
sdsgmftckyadyisrdkpitftqhqmplfrkkmvweilhqqll

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2io1D (D:)
gshmndhinlkvagqdgsvvqfkikrhtplsklmkaycerqglsmrqirfrfdgqpinet
dtpaqlemededtidvfqqqtggvpesslaghsf

    Sequence, based on observed residues (ATOM records): (download) 
    >2io1D (D:)
dhinlkvagqdgsvvqfkikrhtplsklmkaycerqglsmrqirfrfdgqpinetdtpaq
lemededtidvfqqqtggvpes

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2io1E (E:)
gshmasdlleltedmekeisnalghgpqdeilssafklritrgdiqtlknyhwlndevin
fymnllvernkkqgypalhvfstffypklksggyqavkrwtkgvnlfeqeiilvpihrkv
hwslvvidlrkkclkyldsmgqkghriceillqylqdesktkrnsdlnllewthhsmkph
eipqqlngsdsgmftckyadyisrdkpitftqhqmplfrkkmvweilhqqll

    Sequence, based on observed residues (ATOM records): (download) 
    >2io1E (E:)
eltedmekeisnalghgpqdeilssafklritrgdiqtlknyhwlndevinfymnllver
nkkqgypalhvfstffypklksggyqavkrwtkgvnlfeqeiilvpihrkvhwslvvidl
rkkclkyldsmgqkghriceillqylqdesktkrnsdlnllewthhsmkpheipqqlngs
dsgmftckyadyisrdkpitftqhqmplfrkkmvweilhqqll

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2io1F (F:)
gshmndhinlkvagqdgsvvqfkikrhtplsklmkaycerqglsmrqirfrfdgqpinet
dtpaqlemededtidvfqqqtggvpesslaghsf

    Sequence, based on observed residues (ATOM records): (download) 
    >2io1F (F:)
dhinlkvagqdgsvvqfkikrhtplsklmkaycerqglsmrqirfrfdgqpinetdtpaq
lemededtidvfqqqtggvpe