PDB entry 2imc

View 2imc on RCSB PDB site
Description: Clostridium botulinum Neurotoxin Serotype A Light Chain, Residues 1-424
Class: hydrolase
Keywords: Clostridium botulinum neurotoxin serotype A, protease inhibitors, substrate specificity, HYDROLASE
Deposited on 2006-10-04, released 2007-06-05
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Botulinum neurotoxin A light-chain
    Species: Clostridium botulinum [TaxId:1491]
    Gene: botA, atx, bna
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7B8V4 (20-End)
      • cloning artifact (10-19)
      • conflict (21)
    Domains in SCOPe 2.07: d2imca2, d2imca3
  • Chain 'B':
    Compound: Botulinum neurotoxin A light-chain
    Species: Clostridium botulinum [TaxId:1491]
    Gene: botA, atx, bna
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7B8V4 (20-End)
      • cloning artifact (10-19)
      • conflict (21)
    Domains in SCOPe 2.07: d2imcb2, d2imcb3
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2imcA (A:)
mgsshhhhhhssglvprgshmqfvnkqfnykdpvngvdiayikipnvgqmqpvkafkihn
kiwviperdtftnpeegdlnpppeakqvpvsyydstylstdnekdnylkgvtklferiys
tdlgrmlltsivrgipfwggstidtelkvidtncinviqpdgsyrseelnlviigpsadi
iqfecksfghevlnltrngygstqyirfspdftfgfeeslevdtnpllgagkfatdpavt
lahelihaghrlygiainpnrvfkvntnayyemsglevsfeelrtfgghdakfidslqen
efrlyyynkfkdiastlnkaksivgttaslqymknvfkekyllsedtsgkfsvdklkfdk
lykmlteiytednfvkffkvlnrktylnfdkavfkinivpkvnytiydgfnlrntnlaan
fngqnteinnmnftklknftglfe

    Sequence, based on observed residues (ATOM records): (download) 
    >2imcA (A:)
ssglvprgshmqfvnkqfnykdpvngvdiayikipqmqpvkafkihnkiwviperdtftn
peegdlnpppeqvpvsyydstylstdnekdnylkgvtklferiystdlgrmlltsivrgi
pfwggstidtelkvidtncinviqpdgsyrseelnlviigpsadiiqfecksfghevlnl
trngygstqyirfspdftfgfeeslgagkfatdpavtlahelihaghrlygiainpnrve
vsfeelrtfgghdakfidslqenefrlyyynkfkdiastlnkaksivgttaslqymknvf
kekyllsedtsgkfsvdklkfdklykmlteiytednfvkffkvlnrktylnfdkavfkin
ivpkvnytiydgfnlrntnlaanfngqnteinnmnftklkn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2imcB (B:)
mgsshhhhhhssglvprgshmqfvnkqfnykdpvngvdiayikipnvgqmqpvkafkihn
kiwviperdtftnpeegdlnpppeakqvpvsyydstylstdnekdnylkgvtklferiys
tdlgrmlltsivrgipfwggstidtelkvidtncinviqpdgsyrseelnlviigpsadi
iqfecksfghevlnltrngygstqyirfspdftfgfeeslevdtnpllgagkfatdpavt
lahelihaghrlygiainpnrvfkvntnayyemsglevsfeelrtfgghdakfidslqen
efrlyyynkfkdiastlnkaksivgttaslqymknvfkekyllsedtsgkfsvdklkfdk
lykmlteiytednfvkffkvlnrktylnfdkavfkinivpkvnytiydgfnlrntnlaan
fngqnteinnmnftklknftglfe

    Sequence, based on observed residues (ATOM records): (download) 
    >2imcB (B:)
ssglvprgshmqfvnkqfnykdpvngvdiayikipnvgqmqpvkafkihnkiwviperdt
ftnpeegdlnpppqvpvsyydstylstdnekdnylkgvtklferiystdlgrmlltsivr
gipfwggstidtelkvidtncinviqpdgsyrseelnlviigpsadiiqfecksfghevl
nltrngygstqyirfspdftfgfeeslevllgagkfatdpavtlahelihaghrlygiai
npnrvfvsfeelrtfgghdakfidslqenefrlyyynkfkdiastlnkaksivgttaslq
ymknvfkekyllsedtsgkfsvdklkfdklykmlteiytednfvkffkvlnrktylnfdk
avfkinivpkvnytiydgfnlrntnlaanfngqnteinnmnftkl