PDB entry 2ibt
View 2ibt on RCSB PDB site
Description: Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing 2-aminopurine at the target position and an abasic site analog at the target base partner position
Class: transferase/DNA
Keywords: DNA, DNA methyltransferase, 2-aminopurine, abasic site analog, base flipping, nucleotide flipping, TRANSFERASE-DNA COMPLEX
Deposited on
2006-09-12, released
2007-05-29
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-10-18, with a file datestamp of
2017-10-13.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: modification methylase taqi
Species: Thermus aquaticus [TaxId:271]
Gene: taqIM
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2ibta1, d2ibta2 - Chain 'B':
Compound: 5'-d(*gp*tp*tp*cp*gp*(2pr)p*tp*gp*tp*c)-3'
Species: synthetic, synthetic
- Chain 'C':
Compound: 5'-d(*gp*ap*cp*ap*(3dr)p*cp*gp*(6ma)p*ap*c)-3'
Species: synthetic, synthetic
- Chain 'D':
Compound: modification methylase taqi
Species: Thermus aquaticus [TaxId:271]
Gene: taqIM
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2ibtd1, d2ibtd2 - Chain 'E':
Compound: 5'-d(*gp*tp*tp*cp*gp*(2pr)p*tp*gp*tp*c)-3'
Species: synthetic, synthetic
- Chain 'F':
Compound: 5'-d(*gp*ap*cp*ap*(3dr)p*cp*gp*(6ma)p*ap*c)-3'
Species: synthetic, synthetic
- Heterogens: NEA, GOL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2ibtA (A:)
mglppllslpsnsaprslgrvetppevvdfmvslaeaprggrvlepacahgpflrafrea
hgtayrfvgveidpkaldlppwaegiladfllwepgeafdlilgnppygivgeaskypih
vfkavkdlykkafstwkgkynlygaflekavrllkpggvlvfvvpatwlvledfallref
laregktsvyylgevfpqkkvsavvirfqksgkglslwdtqesesgftpilwaeyphweg
eiirfeteetrkleisgmplgdlfhirfaarspefkkhpavrkepgpglvpvltgrnlkp
gwvdyeknhsglwmpkerakelrdfyatphlvvahtkgtrvvaawderaypwreefhllp
kegvrldpsslvqwlnseamqkhvrtlyrdfvphltlrmlerlpvrreygfhtspesarn
f
Sequence, based on observed residues (ATOM records): (download)
>2ibtA (A:)
vetppevvdfmvslaeaprggrvlepacahgpflrafreahgtayrfvgveidpkaldlp
pwaegiladfllwepgeafdlilgnppygivgeaskypihvfkavkdlykkafstwkgky
nlygaflekavrllkpggvlvfvvpatwlvledfallreflaregktsvyylgevfpqkk
vsavvirfqksgkglslwdtqesesgftpilwaeyphwegeiirfeteetrkleisgmpl
gdlfhirfaarspefkkhpavrkepgpglvpvltgrnlkpgwvdyeknhsglwmpkerak
elrdfyatphlvvahtkgtrvvaawderaypwreefhllpkegvrldpsslvqwlnseam
qkhvrtlyrdfvphltlrmlerlpvrreygfht
- Chain 'B':
No sequence available.
- Chain 'C':
No sequence available.
- Chain 'D':
Sequence, based on SEQRES records: (download)
>2ibtD (D:)
mglppllslpsnsaprslgrvetppevvdfmvslaeaprggrvlepacahgpflrafrea
hgtayrfvgveidpkaldlppwaegiladfllwepgeafdlilgnppygivgeaskypih
vfkavkdlykkafstwkgkynlygaflekavrllkpggvlvfvvpatwlvledfallref
laregktsvyylgevfpqkkvsavvirfqksgkglslwdtqesesgftpilwaeyphweg
eiirfeteetrkleisgmplgdlfhirfaarspefkkhpavrkepgpglvpvltgrnlkp
gwvdyeknhsglwmpkerakelrdfyatphlvvahtkgtrvvaawderaypwreefhllp
kegvrldpsslvqwlnseamqkhvrtlyrdfvphltlrmlerlpvrreygfhtspesarn
f
Sequence, based on observed residues (ATOM records): (download)
>2ibtD (D:)
vetppevvdfmvslaeaprggrvlepacahgpflrafreahgtayrfvgveidpkaldlp
pwaegiladfllwepgeafdlilgnppygivgeaskypihvfkavkdlykkafstwkgky
nlygaflekavrllkpggvlvfvvpatwlvledfallreflaregktsvyylgevfpqkk
vsavvirfqksgkglslwdtqesesgftpilwaeyphwegeiirfeteetrkleisgmpl
gdlfhirfaarspefkkhpavrkepgpglvpvltgrnlkpgwvdyeknhsglwmpkerak
elrdfyatphlvvahtkgtrvvaawderaypwreefhllpkegvrldpsslvqwlnseam
qkhvrtlyrdfvphltlrmlerlpvrreygfht
- Chain 'E':
No sequence available.
- Chain 'F':
No sequence available.