PDB entry 2i9b

View 2i9b on RCSB PDB site
Description: Crystal structure of ATF-urokinase receptor complex
Class: hydrolase
Keywords: urokinase receptor, kringle domain, growth factor-like domain
Deposited on 2006-09-05, released 2007-01-02
The last revision prior to the SCOP 1.75 freeze date was dated 2007-01-09, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.224
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: urokinase-type plasminogen activator
    Species: HOMO SAPIENS
    Gene: PLAU
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2i9ba1, d2i9ba2
  • Chain 'B':
    Compound: urokinase-type plasminogen activator
    Species: HOMO SAPIENS
    Gene: PLAU
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2i9bb1, d2i9bb2
  • Chain 'C':
    Compound: urokinase-type plasminogen activator
    Species: HOMO SAPIENS
    Gene: PLAU
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2i9bc1, d2i9bc2
  • Chain 'D':
    Compound: urokinase-type plasminogen activator
    Species: HOMO SAPIENS
    Gene: PLAU
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2i9bd1, d2i9bd2
  • Chain 'E':
    Compound: Urokinase plasminogen activator surface receptor
    Species: HOMO SAPIENS
    Gene: PLAUR, MO3, UPAR
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q03405 (2-278)
      • cloning artifact (1)
      • engineered (163)
      • engineered (173)
      • engineered (201)
      • engineered (234)
    Domains in SCOP 1.75: d2i9be1, d2i9be2, d2i9be3
  • Chain 'F':
    Compound: Urokinase plasminogen activator surface receptor
    Species: HOMO SAPIENS
    Gene: PLAUR, MO3, UPAR
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q03405 (2-278)
      • cloning artifact (1)
      • engineered (163)
      • engineered (173)
      • engineered (201)
      • engineered (234)
    Domains in SCOP 1.75: d2i9bf1, d2i9bf2, d2i9bf3
  • Chain 'G':
    Compound: Urokinase plasminogen activator surface receptor
    Species: HOMO SAPIENS
    Gene: PLAUR, MO3, UPAR
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q03405 (2-278)
      • engineered (163)
      • engineered (173)
      • engineered (201)
      • engineered (234)
    Domains in SCOP 1.75: d2i9bg1, d2i9bg2, d2i9bg3
  • Chain 'H':
    Compound: Urokinase plasminogen activator surface receptor
    Species: HOMO SAPIENS
    Gene: PLAUR, MO3, UPAR
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q03405 (2-278)
      • engineered (163)
      • engineered (173)
      • engineered (201)
      • engineered (234)
    Domains in SCOP 1.75: d2i9bh1, d2i9bh2, d2i9bh3
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2i9bA (A:)
rssnelhqvpsncdclnggtcvsnkyfsnihwcncpkkfggqhceidksktcyegnghfy
rgkastdtmgrpclpwnsatvlqqtyhahrsdalqlglgkhnycrnpdnrrrpwcyvqvg
lkplvqecmvhdcadgkkpssppee

    Sequence, based on observed residues (ATOM records): (download) 
    >2i9bA (A:)
cdclnggtcvsnkyfsnihwcncpkkfggqhceidksktcyegnghfyrgkastdtmgrp
clpwnsatvlqqtyhahrsdalqlglgkhnycrnpdnrrrpwcyvqvglkplvqecmvhd
ca

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2i9bB (B:)
rssnelhqvpsncdclnggtcvsnkyfsnihwcncpkkfggqhceidksktcyegnghfy
rgkastdtmgrpclpwnsatvlqqtyhahrsdalqlglgkhnycrnpdnrrrpwcyvqvg
lkplvqecmvhdcadgkkpssppee

    Sequence, based on observed residues (ATOM records): (download) 
    >2i9bB (B:)
cdclnggtcvsnkyfsnihwcncpkkfggqhceidksktcyegnghfyrgkastdtmgrp
clpwnsatvlqqtyhahrsdalqlglgkhnycrnpdnrrrpwcyvqvglkplvqecmvhd
ca

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2i9bC (C:)
rssnelhqvpsncdclnggtcvsnkyfsnihwcncpkkfggqhceidksktcyegnghfy
rgkastdtmgrpclpwnsatvlqqtyhahrsdalqlglgkhnycrnpdnrrrpwcyvqvg
lkplvqecmvhdcadgkkpssppee

    Sequence, based on observed residues (ATOM records): (download) 
    >2i9bC (C:)
cdclnggtcvsnkyfsnihwcncpkkfggqhceidksktcyegnghfyrgkastdtmgrp
clpwnsatvlqqtyhahrsdalqlglgkhnycrnpdnrrrpwcyvqvglkplvqecmvhd
ca

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2i9bD (D:)
rssnelhqvpsncdclnggtcvsnkyfsnihwcncpkkfggqhceidksktcyegnghfy
rgkastdtmgrpclpwnsatvlqqtyhahrsdalqlglgkhnycrnpdnrrrpwcyvqvg
lkplvqecmvhdcadgkkpssppee

    Sequence, based on observed residues (ATOM records): (download) 
    >2i9bD (D:)
cdclnggtcvsnkyfsnihwcncpkkfggqhceidksktcyegnghfyrgkastdtmgrp
clpwnsatvlqqtyhahrsdalqlglgkhnycrnpdnrrrpwcyvqvglkplvqecmvhd
ca

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2i9bE (E:)
rslrcmqcktngdcrveecalgqdlcrttivrlweegeelelvekscthsektnrtlsyr
tglkitsltevvcgldlcnqgnsgravtysrsryleciscgssdmscergrhqslqcrsp
eeqcldvvthwiqegeegrpkddrhlrgcgylpgcpgsngfhnqdtfhflkccqttkcne
gpilelenlpqngrqcysckgqsthgcsseetflidcrgpmnqclvatgthepkqqsymv
rgcatasmcqhahlgdafsmnhidvscctksgcnhpdld

    Sequence, based on observed residues (ATOM records): (download) 
    >2i9bE (E:)
slrcmqcktngdcrveecalgqdlcrttivrlweegeelelvekscthsektnrtlsyrt
glkitsltevvcgldlcnqgnsgravtysrsryleciscgssdmschqslqcrspeeqcl
dvvthwiqrpkddrhlrgcgylpgcpgsngfhnqdtfhflkccqttkcnegpilelenlp
qngrqcysckgqsthgcsseetflidcrgpmnqclvatgthepkqqsymvrgcatasahl
gdafsmnhidvscctksgcnhpdld

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2i9bF (F:)
rslrcmqcktngdcrveecalgqdlcrttivrlweegeelelvekscthsektnrtlsyr
tglkitsltevvcgldlcnqgnsgravtysrsryleciscgssdmscergrhqslqcrsp
eeqcldvvthwiqegeegrpkddrhlrgcgylpgcpgsngfhnqdtfhflkccqttkcne
gpilelenlpqngrqcysckgqsthgcsseetflidcrgpmnqclvatgthepkqqsymv
rgcatasmcqhahlgdafsmnhidvscctksgcnhpdld

    Sequence, based on observed residues (ATOM records): (download) 
    >2i9bF (F:)
slrcmqcktngdcrveecalgqdlcrttivrlweegeelelvekscthsektnrtlsyrt
glkitsltevvcgldlcnqgnsgravtysrsryleciscgssdmschqslqcrspeeqcl
dvvthwiqrpkddrhlrgcgylpgcpgsngfhnqdtfhflkccqttkcnegpilelenlp
qngrqcysckgqsthgcsseetflidcrgpmnqclvatgthepkqqsymvrgcatasahl
gdafsmnhidvscctksgcnhpdld

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2i9bG (G:)
rslrcmqcktngdcrveecalgqdlcrttivrlweegeelelvekscthsektnrtlsyr
tglkitsltevvcgldlcnqgnsgravtysrsryleciscgssdmscergrhqslqcrsp
eeqcldvvthwiqegeegrpkddrhlrgcgylpgcpgsngfhnqdtfhflkccqttkcne
gpilelenlpqngrqcysckgqsthgcsseetflidcrgpmnqclvatgthepkqqsymv
rgcatasmcqhahlgdafsmnhidvscctksgcnhpdld

    Sequence, based on observed residues (ATOM records): (download) 
    >2i9bG (G:)
lrcmqcktngdcrveecalgqdlcrttivrlgeelelvekscthsektnrtlsyrtglki
tsltevvcgldlcnqgnsgeciscgssdmschqslqcrspeeqcldvvthwiqkddrhlr
gcgylpgcpgsngfhnqdtfhflkccqttkcnegpilelenlpqngrqcysckgqsthgc
sseetflidcrgpmnqclvatgthepkqqsymvrgcatasahlgdafsmnhidvscctks
gcnhpdld

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2i9bH (H:)
rslrcmqcktngdcrveecalgqdlcrttivrlweegeelelvekscthsektnrtlsyr
tglkitsltevvcgldlcnqgnsgravtysrsryleciscgssdmscergrhqslqcrsp
eeqcldvvthwiqegeegrpkddrhlrgcgylpgcpgsngfhnqdtfhflkccqttkcne
gpilelenlpqngrqcysckgqsthgcsseetflidcrgpmnqclvatgthepkqqsymv
rgcatasmcqhahlgdafsmnhidvscctksgcnhpdld

    Sequence, based on observed residues (ATOM records): (download) 
    >2i9bH (H:)
lrcmqcktngdcrveecalgqdlcrttivrlgeelelvekscthsektnrtlsyrtglki
tsltevvcgldlcnqgnsgeciscgssdmschqslqcrspeeqcldvvthwiqkddrhlr
gcgylpgcpgsngfhnqdtfhflkccqttkcnegpilelenlpqngrqcysckgqsthgc
sseetflidcrgpmnqclvatgthepkqqsymvrgcatasahlgdafsmnhidvscctks
gcnhpdld