PDB entry 2i0g

View 2i0g on RCSB PDB site
Description: Benzopyrans are Selective Estrogen Receptor beta Agonists (SERBAs) with Novel Activity in Models of Benign Prostatic Hyperplasia
Class: transcription
Keywords: nuclear receptor, ligand binding domain
Deposited on 2006-08-10, released 2006-10-24
The last revision prior to the SCOP 1.75 freeze date was dated 2006-10-24, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.235
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Estrogen receptor beta
    Species: HOMO SAPIENS
    Gene: ESR2, ESTRB, NR3A2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2i0ga1
  • Chain 'B':
    Compound: Estrogen receptor beta
    Species: HOMO SAPIENS
    Gene: ESR2, ESTRB, NR3A2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2i0gb1
  • Heterogens: I0G, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2i0gA (A:)
mhhhhhhrellldalspeqlvltlleaepphvlisrpsapfteasmmmsltkladkelvh
miswakkipgfvelslfdqvrllescwmevlmmglmwrsidhpgklifapdlvldrdegk
cvegileifdmllattsrfrelklqhkeylcvkamillnssmyplvtatqdadssrklah
llnavtdalvwviaksgissqqqsmrlanllmllshvrhasnkgmehllnmkcknvvpvy
dlllemlnahvlrgcks

    Sequence, based on observed residues (ATOM records): (download) 
    >2i0gA (A:)
dalspeqlvltlleaepphvlisrpasmmmsltkladkelvhmiswakkipgfvelslfd
qvrllescwmevlmmglmwrsidhpgklifapdlvldrdegkcvegileifdmllattsr
frelklqhkeylcvkamillnssmyplvssrklahllnavtdalvwviaksgissqqqsm
rlanllmllshvrhasnkgmehllnmkvpvydlllemlnah

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2i0gB (B:)
mhhhhhhrellldalspeqlvltlleaepphvlisrpsapfteasmmmsltkladkelvh
miswakkipgfvelslfdqvrllescwmevlmmglmwrsidhpgklifapdlvldrdegk
cvegileifdmllattsrfrelklqhkeylcvkamillnssmyplvtatqdadssrklah
llnavtdalvwviaksgissqqqsmrlanllmllshvrhasnkgmehllnmkcknvvpvy
dlllemlnahvlrgcks

    Sequence, based on observed residues (ATOM records): (download) 
    >2i0gB (B:)
ldalspeqlvltlleaepphvlisrpasmmmsltkladkelvhmiswakkipgfvelslf
dqvrllescwmevlmmglmwrsidhpgklifapdlvldrdegkcvegileifdmllatts
rfrelklqhkeylcvkamillnssmyplvssrklahllnavtdalvwviaksgissqqqs
mrlanllmllshvrhasnkgmehllnmkvpvydlllemlnah