PDB entry 2hzy

View 2hzy on RCSB PDB site
Description: Mouse fumarylacetoacetate hydrolase complexes with a transition-state mimic of the complete substrate
Class: hydrolase
Keywords: transition-state mimicking complex
Deposited on 2006-08-09, released 2006-08-22
The last revision prior to the SCOP 1.75 freeze date was dated 2007-05-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.35 Å
R-factor: 0.169
AEROSPACI score: 0.83 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fumarylacetoacetase
    Species: MUS MUSCULUS
    Gene: Fah
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2hzya1, d2hzya2
  • Chain 'B':
    Compound: Fumarylacetoacetase
    Species: MUS MUSCULUS
    Gene: Fah
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35505 (2-End)
      • cloning artifact (0-1)
    Domains in SCOP 1.75: d2hzyb1, d2hzyb2
  • Heterogens: NA, MN, NI, CA, DHJ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2hzyA (A:)
gsmsfipvaedsdfpiqnlpygvfstqsnpkprigvaigdqildlsvikhlftgpalskh
qhvfdettlnnfmglgqaawkearaslqnllsasqarlrddkelrqraftsqasatmhlp
atigdytdfyssrqhatnvgimfrgkenallpnwlhlpvgyhgrassivvsgtpirrpmg
qmrpdnskppvygacrlldmelemaffvgpgnrfgepipiskahehifgmvlmndwsard
iqqweyvplgpflgksfgttispwvvpmdalmpfvvpnpkqdpkplpylchsqpytfdin
lsvslkgegmsqaaticrsnfkhmywtmlqqlthhsvngcnlrpgdllasgtisgsdpes
fgsmlelswkgtkaidvgqgqtrtflldgdeviitghcqgdgyrvgfgqcagkvlpalsp
a

    Sequence, based on observed residues (ATOM records): (download) 
    >2hzyA (A:)
msfipvaedsdfpiqnlpygvfstqsnpkprigvaigdqildlsvikhlftgpalskhqh
vfdettlnnfmglgqaawkearaslqnllsasqarlrddkelrqraftsqasatmhlpat
igdytdfyssrqhatnvgimfrgkenallpnwlhlpvgyhgrassivvsgtpirrpmgqm
rpdnskppvygacrlldmelemaffvgpgnrfgepipiskahehifgmvlmndwsardiq
qweyvplgpflgksfgttispwvvpmdalmpfvvpnpkqdpkplpylchsqpytfdinls
vslkgegmsqaaticrsnfkhmywtmlqqlthhsvngcnlrpgdllasgtisgsdpesfg
smlelswkgtkaidvgqgqtrtflldgdeviitghcqgdgyrvgfgqcagkvlpal

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2hzyB (B:)
gsmsfipvaedsdfpiqnlpygvfstqsnpkprigvaigdqildlsvikhlftgpalskh
qhvfdettlnnfmglgqaawkearaslqnllsasqarlrddkelrqraftsqasatmhlp
atigdytdfyssrqhatnvgimfrgkenallpnwlhlpvgyhgrassivvsgtpirrpmg
qmrpdnskppvygacrlldmelemaffvgpgnrfgepipiskahehifgmvlmndwsard
iqqweyvplgpflgksfgttispwvvpmdalmpfvvpnpkqdpkplpylchsqpytfdin
lsvslkgegmsqaaticrsnfkhmywtmlqqlthhsvngcnlrpgdllasgtisgsdpes
fgsmlelswkgtkaidvgqgqtrtflldgdeviitghcqgdgyrvgfgqcagkvlpalsp
a

    Sequence, based on observed residues (ATOM records): (download) 
    >2hzyB (B:)
gsmsfipvaedsdfpiqnlpygvfstqsnpkprigvaigdqildlsvikhlftgpalskh
qhvfdettlnnfmglgqaawkearaslqnllsasqarlrddkelrqraftsqasatmhlp
atigdytdfyssrqhatnvgimfrgkenallpnwlhlpvgyhgrassivvsgtpirrpmg
qmrpdnskppvygacrlldmelemaffvgpgnrfgepipiskahehifgmvlmndwsard
iqqweyvplgpflgksfgttispwvvpmdalmpfvvpnpkqdpkplpylchsqpytfdin
lsvslkgegmsqaaticrsnfkhmywtmlqqlthhsvngcnlrpgdllasgtisgsdpes
fgsmlelswkgtkaidvgqgqtrtflldgdeviitghcqgdgyrvgfgqcagkvlpal