PDB entry 2hwc

View 2hwc on RCSB PDB site
Description: a comparison of the anti-rhinoviral drug binding pocket in hrv14 and hrv1a
Class: Virus
Keywords: RHINOVIRUS COAT PROTEIN, Icosahedral virus, Virus
Deposited on 1994-01-25, released 1994-11-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-02-29, with a file datestamp of 2012-02-24.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain '1':
    Compound: human rhinovirus 14 coat protein (subunit vp1)
    Species: Human rhinovirus B [TaxId:12131]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2hwc1_
  • Chain '2':
    Compound: human rhinovirus 14 coat protein (subunit vp2)
    Species: Human rhinovirus B [TaxId:12131]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03303 (Start-261)
      • conflict (169)
    Domains in SCOPe 2.08: d2hwc.1
  • Chain '3':
    Compound: human rhinovirus 14 coat protein (subunit vp3)
    Species: Human rhinovirus B [TaxId:12131]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2hwc3_
  • Chain '4':
    Compound: human rhinovirus 14 coat protein (subunit vp4)
    Species: Human rhinovirus B [TaxId:12131]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2hwc.1
  • Heterogens: W54

PDB Chain Sequences:

  • Chain '1':
    Sequence, based on SEQRES records: (download) 
    >2hwc1 (1:)
glgdeleevivektkqtvasissgpkhtqkvpiltanetgatmpvlpsdsietrttymhf
ngsetdvecflgraacvhvteiqnkdatgidnhreaklfndwkinlsslvqlrkklelft
yvrfdseytilatasqpdsanyssnlvvqamyvppgapnpkewddytwqsasnpsvffkv
gdtsrfsvpyvglasayncfydgyshddaetqygitvlnhmgsmafrivnehdehktlvk
irvyhrakhveawiprapralpytsigrtnypkntepvikkrkgdiksy

    Sequence, based on observed residues (ATOM records): (download) 
    >2hwc1 (1:)
tvasissgpkhtqkvpiltanetgatmpvlpsdsietrttymhfngsetdvecflgraac
vhvteiqnkdatgidnhreaklfndwkinlsslvqlrkklelftyvrfdseytilatasq
pdsanyssnlvvqamyvppgapnpkewddytwqsasnpsvffkvgdtsrfsvpyvglasa
yncfydgyshddaetqygitvlnhmgsmafrivnehdehktlvkirvyhrakhveawipr
apralpytsigrtnypkntepvikkrkgdiksy

  • Chain '2':
    Sequence, based on SEQRES records: (download) 
    >2hwc2 (2:)
spnveacgysdrvqqitlgnstittqeaanavvcyaewpeylpdvdasdvnktskpdtsv
crfytldsktwttgskgwcwklpdalkdmgvfgqnmffhslgrsgytvhvqcnatkfhsg
cllvvvipehqlasheggnvsvkytfthpgergidlssanevggpvkdvvynmngtllgn
llifphqfinlrtnntativipyinsvpidsmtrhnnvslmvipiapltvptgatpslpi
tvtiapmctefsgirsksivpq

    Sequence, based on observed residues (ATOM records): (download) 
    >2hwc2 (2:)
gysdrvqqitlgnstittqeaanavvcyaewpeylpdvdasdvnktskpdtsvcrfytld
sktwttgskgwcwklpdalkdmgvfgqnmffhslgrsgytvhvqcnatkfhsgcllvvvi
pehqlasheggnvsvkytfthpgergidlssanevggpvkdvvynmngtllgnllifphq
finlrtnntativipyinsvpidsmtrhnnvslmvipiapltvptgatpslpitvtiapm
ctefsgirsksivpq

  • Chain '3':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2hwc3 (3:)
glptttlpgsgqflttddrqspsalpnyeptprihipgkvhnlleiiqvdtlipmnntht
kdevnsyliplnanrqneqvfgtnlfigdgvfkttllgeivqyythwsgslrfslmytgp
alssaklilaytppgargpqdrreamlgthvvwdiglqstivmtipwtsgvqfrytdpdt
ytsagflscwyqtslilppettgqvyllsfisacpdfklrlmkdtqtisqtvalte

  • Chain '4':
    Sequence, based on SEQRES records: (download) 
    >2hwc4 (4:)
gaqvstqksgshenqniltngsnqtftvinyykdaastssagqslsmdpskftepvkdlm
lkgapaln

    Sequence, based on observed residues (ATOM records): (download) 
    >2hwc4 (4:)
inyykdaastssagqslsmdpskftepvkdlmlkgapaln