PDB entry 2hth

View 2hth on RCSB PDB site
Description: Structural basis for ubiquitin recognition by the human EAP45/ESCRT-II GLUE domain
Class: protein transport
Keywords: GLUE domain, PH domain, Protein sorting, viral budding, Ubiquitin complex, PROTEIN TRANSPORT
Deposited on 2006-07-25, released 2006-10-24
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.252
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Gene: RPS27A, UBA52, UBB, UBC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2htha_
  • Chain 'B':
    Compound: vacuolar protein sorting protein 36
    Species: Homo sapiens [TaxId:9606]
    Gene: VPS36, C13orf9, EAP45
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2hthb1

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2hthA (A:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrgg
    

    Sequence, based on observed residues (ATOM records): (download)
    >2hthA (A:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrl
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2hthB (B:)
    ghmdrfvwtsglleinetlviqqrgvriydgeekikfdagtlllsthrliwrdqknhecc
    maillsqivfieeqaagigksakivvhlhpappnkepgpfqssknsyiklsfkehgqief
    yrrlseemtqrrwenmpvsq
    

    Sequence, based on observed residues (ATOM records): (download)
    >2hthB (B:)
    rfvwtsglleinetlviqqrgvriydgeekikfdagtlllsthrliwrdqknheccmail
    lsqivfieeqaagigksakivvhlhpappnkepgpfqssknsyiklsfkehgqiefyrrl
    seemtqrrw