PDB entry 2hof

View 2hof on RCSB PDB site
Description: Crystal structure of the pre-cleavage synaptic complex in the cre-loxp site-specific recombination
Class: recombination/DNA
Keywords: CRE-LOXP PRECLEAVAGE SYNAPSE, recombination/DNA COMPLEX
Deposited on 2006-07-14, released 2007-06-26
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.24
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Recombinase cre
    Species: Enterobacteria phage P1 [TaxId:10678]
    Gene: cre
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2hofa1, d2hofa2
  • Chain 'B':
    Compound: Recombinase cre
    Species: Enterobacteria phage P1 [TaxId:10678]
    Gene: cre
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06956
      • engineered (200)
    Domains in SCOPe 2.01: d2hofb1, d2hofb2
  • Chain 'C':
    Compound: LoxP DNA
  • Chain 'D':
    Compound: LoxP DNA
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2hofA (A:)
msnlltvhqnlpalpvdatsdevrknlmdmfrdrqafsehtwkmllsvcrswaawcklnn
rkwfpaepedvrdyllylqarglavktiqqhlgqlnmlhrrsglprpsdsnavslvmrri
rkenvdagerakqalafertdfdqvrslmensdrcqdirnlaflgiayntllriaeiari
rvkdisrtdggrmlihigrtatlvstagvekalslgvtklverwisvsgvaddpnnylfc
rvrkngvaapsatsqlstralegifeathrliygakddsgqrylawsghsarvgaardma
ragvsipeimqaggwtnvnivmnyirnldsetgamvrlledgd

    Sequence, based on observed residues (ATOM records): (download) 
    >2hofA (A:)
sdevrknlmdmfrdrqafsehtwkmllsvcrswaawcklnnrkwfpaepedvrdyllylq
arglavktiqqhlgqlnmlhrrsglprpsdsnavslvmrrirkenvdagerakqalafer
tdfdqvrslmensdrcqdirnlaflgiayntllriaeiarirvkdisrtdggrmlihika
lslgvtklverwisvsgvaddpnnylfcrvrkngvaapsatsqlstralegifeathrli
ygakddsgqrylawsghsarvgaardmaragvsipeimqaggwtnvnivmnyirnldset
gamvrlled

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2hofB (B:)
msnlltvhqnlpalpvdatsdevrknlmdmfrdrqafsehtwkmllsvcrswaawcklnn
rkwfpaepedvrdyllylqarglavktiqqhlgqlnmlhrrsglprpsdsnavslvmrri
rkenvdagerakqalafertdfdqvrslmensdrcqdirnlaflgiayntllriaeiari
rvkdisrtdggrmlihigrtatlvstagvekalslgvtklverwisvsgvaddpnnylfc
rvrkngvaapsatsqlstralegifeathrliygakddsgqrylawsghsarvgaardma
ragvsipeimqaggwtnvnivmnyirnldsetgamvrlledgd

    Sequence, based on observed residues (ATOM records): (download) 
    >2hofB (B:)
sdevrknlmdmfrdrqafsehtwkmllsvcrswaawcklnnrkwfpaepedvrdyllylq
arglavktiqqhlgqlnmlhrrsglprpsdsnavslvmrrirkenvdagerakqalafer
tdfdqvrslmensdrcqdirnlaflgiayntllriaeiarirvkdisrtdggrmlihigr
tatlvstagvekalslgvtklverwisvsgvaddpnnylfcrvrkngvaapsatsqlstr
alegifeathrliygakddsgqrylawsghsarvgaardmaragvsipeimqaggwtnvn
ivmnyirnamvrlled

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.