PDB entry 2hfw
View 2hfw on RCSB PDB site
Description: Structural and kinetic analysis of proton shuttle residues in the active site of human carbonic anhydrase III
Class: lyase
Keywords: proton shuttle, HCA III, proton transfer, LYASE
Deposited on
2006-06-26, released
2007-05-08
The last revision prior to the SCOPe 2.02 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.204
AEROSPACI score: 0.28
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Carbonic anhydrase 3
Species: Homo sapiens [TaxId:9606]
Gene: CA3
Database cross-references and differences (RAF-indexed):
- Uniprot P07451 (Start-258)
- engineered (63)
- engineered (66)
- engineered (180)
- engineered (186)
Domains in SCOPe 2.02: d2hfwa_ - Heterogens: ZN, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2hfwA (A:)
makewgyashngpdhwhelfpnakgenqspielhtkdirhdpslqpwsvsydggsaktil
nnghtcnvvfddtydrsmlrggplpgpyrlrqfhlhwgssddhgsehtvdgvkyaaelhl
vhwnpkyntfkealkqrdgiavigiflkighengefqifldaldkiktkgkeapftkfdp
sslfpasrdywtyqgsfttppceecivwlllkepmtvssdqmaklrsllssaeneppvpl
vsnwrppqpinnrvvrasfk
Sequence, based on observed residues (ATOM records): (download)
>2hfwA (A:)
ewgyashngpdhwhelfpnakgenqspielhtkdirhdpslqpwsvsydggsaktilnng
htcnvvfddtydrsmlrggplpgpyrlrqfhlhwgssddhgsehtvdgvkyaaelhlvhw
npkyntfkealkqrdgiavigiflkighengefqifldaldkiktkgkeapftkfdpssl
fpasrdywtyqgsfttppceecivwlllkepmtvssdqmaklrsllssaeneppvplvsn
wrppqpinnrvvrasfk