PDB entry 2hck

View 2hck on RCSB PDB site
Description: src family kinase hck-quercetin complex
Class: transferase
Keywords: transferase, protein tyrosine kinase, signal transduction, sh2, sh3
Deposited on 1997-02-25, released 1997-08-20
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.228
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hematopoetic cell kinase hck
    Species: Homo sapiens [TaxId:9606]
    Gene: HUMAN HCK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08631 (0-437)
      • modified residue (433)
    Domains in SCOPe 2.06: d2hcka1, d2hcka2, d2hcka3
  • Chain 'B':
    Compound: hematopoetic cell kinase hck
    Species: Homo sapiens [TaxId:9606]
    Gene: HUMAN HCK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08631 (0-437)
      • modified residue (433)
    Domains in SCOPe 2.06: d2hckb1, d2hckb2, d2hckb3
  • Heterogens: CA, QUE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2hckA (A:)
ediivvalydyeaihhedlsfqkgdqmvvleesgewwkarslatrkegyipsnyvarvds
leteewffkgisrkdaerqllapgnmlgsfmirdsettkgsyslsvrdydprqgdtvkhy
kirtldnggfyisprstfstlqelvdhykkgndglcqklsvpcmsskpqkpwekdaweip
reslklekklgagqfgevwmatynkhtkvavktmkpgsmsveaflaeanvmktlqhdklv
klhavvtkepiyiitefmakgslldflksdegskqplpklidfsaqiaegmafieqrnyi
hrdlraanilvsaslvckiadfglarvgakfpikwtapeainfgsftiksdvwsfgillm
eivtygripypgmsnpeviralergyrmprpencpeelynimmrcwknrpeerptfeyiq
svlddfytatesqyqqqp

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2hckB (B:)
ediivvalydyeaihhedlsfqkgdqmvvleesgewwkarslatrkegyipsnyvarvds
leteewffkgisrkdaerqllapgnmlgsfmirdsettkgsyslsvrdydprqgdtvkhy
kirtldnggfyisprstfstlqelvdhykkgndglcqklsvpcmsskpqkpwekdaweip
reslklekklgagqfgevwmatynkhtkvavktmkpgsmsveaflaeanvmktlqhdklv
klhavvtkepiyiitefmakgslldflksdegskqplpklidfsaqiaegmafieqrnyi
hrdlraanilvsaslvckiadfglarvgakfpikwtapeainfgsftiksdvwsfgillm
eivtygripypgmsnpeviralergyrmprpencpeelynimmrcwknrpeerptfeyiq
svlddfytatesqyqqqp