PDB entry 2h2g

View 2h2g on RCSB PDB site
Description: The Structural Basis of Sirtuin substrate affinity
Class: hydrolase
Keywords: H3-K115AC, SIR2, SIR2TM, SIRTUIN, SIRT1, HISTONE H3, Hydrolase
Deposited on 2006-05-18, released 2006-11-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 1.63 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NAD-dependent deacetylase
    Species: Thermotoga maritima [TaxId:2336]
    Gene: npdA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2h2ga_
  • Chain 'B':
    Compound: histone h3 peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2h2gA (A:)
mkmkefldllnesrltvtltgagistpsgipdfrgpngiykkysqnvfdidffyshpeef
yrfakegifpmlqakpnlahvllakleekglieavitqnidrlhqragskkvielhgnve
eyycvrcekkytvedvikklessdvplcddcnslirpnivffgenlpqdalreaiglssr
aslmivlgsslvvypaaelplitvrsggklvivnlgetpfddiatlkynmdvvefarrvm
eeggis

    Sequence, based on observed residues (ATOM records): (download) 
    >2h2gA (A:)
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pmlqakpnlahvllakleekglieavitqnidrlhqragskkvielhgnveeyycvrcek
kytvedvikklessdvplcddcnslirpnivffgenlpqdalreaiglssraslmivlgs
slvvypaaelplitvrsggklvivnlgetpfddiatlkynmdvvefarrvmeeggi

  • Chain 'B':
    No sequence available.