PDB entry 2h10
View 2h10 on RCSB PDB site
Description: Crystal structure of the M69V E166A double mutant of SHV-1 b-lactamase complexed to tazobactam
Class: hydrolase
Keywords: antibiotic resistance, b-lactamase inhibitor, HYDROLASE
Deposited on
2006-05-15, released
2007-01-30
The last revision prior to the SCOPe 2.04 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.159
AEROSPACI score: 0.58
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Beta-lactamase SHV-1
Species: Klebsiella pneumoniae [TaxId:573]
Gene: bla, shv1
Database cross-references and differences (RAF-indexed):
- Uniprot P0AD64 (0-262)
- engineered (43)
- engineered (140)
Domains in SCOPe 2.04: d2h10a_ - Heterogens: TBE, MA4, HOH