PDB entry 2gys

View 2gys on RCSB PDB site
Description: 2.7 A structure of the extracellular domains of the human beta common receptor involved in IL-3, IL-5, and GM-CSF signalling
Class: signaling protein, cytokine
Keywords: dimer of interlocking chains of fibronectin-III domains, four fibronectin-III domains per chain, signaling protein, cytokine
Deposited on 2006-05-09, released 2006-06-20
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.214
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cytokine receptor common beta chain
    Species: Homo sapiens [TaxId:9606]
    Gene: CSF2RB, IL3RB, IL5RB
    Database cross-references and differences (RAF-indexed):
    • GB CAG30314 (0-End)
      • engineered (327)
    Domains in SCOPe 2.06: d2gysa1, d2gysa2, d2gysa3, d2gysa4
  • Chain 'B':
    Compound: cytokine receptor common beta chain
    Species: Homo sapiens [TaxId:9606]
    Gene: CSF2RB, IL3RB, IL5RB
    Database cross-references and differences (RAF-indexed):
    • GB CAG30314 (0-End)
      • engineered (327)
    Domains in SCOPe 2.06: d2gysb1, d2gysb2, d2gysb3, d2gysb4

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2gysA (A:)
eetiplqtlrcyndytshitcrwadtqdaqrlvnvtlirrvnedllepvscdlsddmpws
acphprcvprrcvipcqsfvvtdvdyfsfqpdrplgtrltvtltqhvqppeprdlqistd
qdhflltwsvalgspqshwlspgdlefevvykrlqdswedaaillsntsqatlgpehlmp
sstyvarvrtrlapgsrlsgrpskwspevcwdsqpgdeaqpqnlecffdgaavlscswev
rkevassvsfglfykpspdagsavllreeecspvlreglgslhtrhhcqipvpdpathgq
yivsvqprraekhikssvniqmappslqvtkdgdsyslrwetmkmryehidhtfeiqyrk
dtatwkdsktetlqnahsmalpalepstrywarvrvrtsrtgyngiwsewsearswdte

    Sequence, based on observed residues (ATOM records): (download) 
    >2gysA (A:)
eetiplqtlrcyndytshitcrwadtqdaqrlvnvtlirrvnedllepvscdlsddmpws
acphprcvprrcvipcqsfvvtdvdyfsfqpdrplgtrltvtltqhvqppeprdlqistd
qdhflltwsvalhwlspgdlefevvykrlqdswedaaillsntsqatlgpehlmpsstyv
arvrtrlapgsrlsgrpskwspevcwdsqpgdeaqpqnlecffdgaavlscswevrkeva
ssvsfglfykpsavllreeecspvlreglgslhtrhhcqipvpdpathgqyivsvqprra
ekhikssvniqmappslqvtdsyslrwetdhtfeiqyrkdtatwkdsktetlqnahsmal
palepstrywarvrvrtsrtgyngiwsewsearswdt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2gysB (B:)
eetiplqtlrcyndytshitcrwadtqdaqrlvnvtlirrvnedllepvscdlsddmpws
acphprcvprrcvipcqsfvvtdvdyfsfqpdrplgtrltvtltqhvqppeprdlqistd
qdhflltwsvalgspqshwlspgdlefevvykrlqdswedaaillsntsqatlgpehlmp
sstyvarvrtrlapgsrlsgrpskwspevcwdsqpgdeaqpqnlecffdgaavlscswev
rkevassvsfglfykpspdagsavllreeecspvlreglgslhtrhhcqipvpdpathgq
yivsvqprraekhikssvniqmappslqvtkdgdsyslrwetmkmryehidhtfeiqyrk
dtatwkdsktetlqnahsmalpalepstrywarvrvrtsrtgyngiwsewsearswdte

    Sequence, based on observed residues (ATOM records): (download) 
    >2gysB (B:)
eetiplqtlrcyndytshitcrwadtqdaqrlvnvtlirrvnedllepvscdlsddmpws
acphprcvprrcvipcqsfvvtdvdyfsfqpdrplgtrltvtltqhvqppeprdlqistd
qdhflltwsvalhwlspgdlefevvykrlqdswedaaillsntsqatlgpehlmpsstyv
arvrtrlapgsrlsgrpskwspevcwdsqpgdeaqpqnlecffdgaavlscswevrkeva
ssvsfglfykpspdreeecspvlreglgslhtrhhcqipvpdpathgqyivsvqprraek
hikssvniqmappslqvtkdgdsyslrwetmkmryehidhtfeiqyrkdtatwkdsktet
lqnahsmalpalepstrywarvrvrtsrtgyngiwsewsearswdt