PDB entry 2gs2

View 2gs2 on RCSB PDB site
Description: Crystal Structure of the active EGFR kinase domain
Class: transferase
Keywords: EGFR, kinase, active
Deposited on 2006-04-25, released 2006-06-20
The last revision prior to the SCOP 1.73 freeze date was dated 2006-06-27, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.205
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Epidermal growth factor receptor
    Species: HOMO SAPIENS
    Gene: EGFR
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2gs2a1
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2gs2A (A:)
gamgeapnqallrilketefkkikvlgsgafgtvykglwipegekvkipvaikelreats
pkankeildeayvmasvdnphvcrllgicltstvqlitqlmpfgclldyvrehkdnigsq
yllnwcvqiakgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhae
ggkvpikwmalesilhriythqsdvwsygvtvwelmtfgskpydgipaseissilekger
lpqppictidvymimvkcwmidadsrpkfreliiefskmardpqrylviqgdermhlpsp
tdsnfyralmdeedmddvvdadeylipqqg

    Sequence, based on observed residues (ATOM records): (download) 
    >2gs2A (A:)
geapnqallrilketefkkikvlgsgafgtvykglwipegekvkipvaikeatspkanke
ildeayvmasvdnphvcrllgicltstvqlitqlmpfgclldyvrehkdnigsqyllnwc
vqiakgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhaeggkvpi
kwmalesilhriythqsdvwsygvtvwelmtfgskpydgipaseissilekgerlpqppi
ctidvymimvkcwmidadsrpkfreliiefskmardpqrylviqgdermhlpdmddvvda
deyli