PDB entry 2goo

View 2goo on RCSB PDB site
Description: Ternary Complex of BMP-2 bound to BMPR-Ia-ECD and ActRII-ECD
Class: transferase
Keywords: TGF-beta, BMP-2, BMPR-Ia, ActRII, ALK-3, TRANSFERASE
Deposited on 2006-04-13, released 2006-05-09
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bone morphogenetic protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: BMP2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2gooa_
  • Chain 'B':
    Compound: Bone morphogenetic protein receptor type IA
    Species: Homo sapiens [TaxId:9606]
    Gene: BMPR1A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2goob_
  • Chain 'C':
    Compound: Activin receptor type 2A
    Species: Mus musculus [TaxId:10090]
    Gene: Acvr2a
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2gooc_
  • Chain 'D':
    Compound: Bone morphogenetic protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: BMP2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2good_
  • Chain 'E':
    Compound: Bone morphogenetic protein receptor type IA
    Species: Homo sapiens [TaxId:9606]
    Gene: BMPR1A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2gooe_
  • Chain 'F':
    Compound: Activin receptor type 2A
    Species: Mus musculus [TaxId:10090]
    Gene: Acvr2a
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2goof_
  • Heterogens: NDG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2gooA (A:)
    qakhkqrkrlkssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnh
    aivqtlvnsvnskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr
    

    Sequence, based on observed residues (ATOM records): (download)
    >2gooA (A:)
    ssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnhaivqtlvnsvn
    skipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2gooB (B:)
    gsqnldsmlhgtgmksdsdqkksengvtlapedtlpflkcycsghcpddainntcitngh
    cfaiieeddqgettlasgcmkyegsdfqckdspkaqlrrtieccrtnlcnqylqptlppv
    vigpffdgsir
    

    Sequence, based on observed residues (ATOM records): (download)
    >2gooB (B:)
    pflkcycsghcpddainntcitnghcfaiieeddqgettlasgcmkyegsdfqckdspka
    qlrrtieccrtnlcnqylqptlppv
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2gooC (C:)
    ailgrsetqeclffnanwerdrtnqtgvepcygdkdkrrhcfatwknisgsieivkqgcw
    lddincydrtdciekkdspevyfcccegnmcnekfsyfpeme
    

    Sequence, based on observed residues (ATOM records): (download)
    >2gooC (C:)
    tqeclffnanwerdrtnqtgvepcygdkdkrrhcfatwknisgsieivkqgcwlddincy
    drtdciekkdspevyfcccegnmcnekfsyfp
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >2gooD (D:)
    qakhkqrkrlkssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnh
    aivqtlvnsvnskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr
    

    Sequence, based on observed residues (ATOM records): (download)
    >2gooD (D:)
    kssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnhaivqtlvnsv
    nskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >2gooE (E:)
    gsqnldsmlhgtgmksdsdqkksengvtlapedtlpflkcycsghcpddainntcitngh
    cfaiieeddqgettlasgcmkyegsdfqckdspkaqlrrtieccrtnlcnqylqptlppv
    vigpffdgsir
    

    Sequence, based on observed residues (ATOM records): (download)
    >2gooE (E:)
    lpflkcycsghcpddainntcitnghcfaiieeddqgettlasgcmkyegsdfqckdspk
    aqlrrtieccrtnlcnqylqptlppvvi
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >2gooF (F:)
    ailgrsetqeclffnanwerdrtnqtgvepcygdkdkrrhcfatwknisgsieivkqgcw
    lddincydrtdciekkdspevyfcccegnmcnekfsyfpeme
    

    Sequence, based on observed residues (ATOM records): (download)
    >2gooF (F:)
    etqeclffnanwerdrtnqtgvepcygdkdkrrhcfatwknisgsieivkqgcwlddinc
    ydrtdciekkdspevyfcccegnmcnekfsyfp