PDB entry 2gj6

View 2gj6 on RCSB PDB site
Description: The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5K-4-[3-Indolyl]-butyric acid) peptide
Class: immune system
Keywords: HTLV-1 TAX peptide, haptenated peptide, Lysine-4-(3-Indolyl)-butyric acid, MHC class I,HLA-A2, T-cell receptor A6, IMMUNE SYSTEM
Deposited on 2006-03-30, released 2006-10-03
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.56 Å
R-factor: 0.202
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, A-2 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-A, HLAA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2gj6a1, d2gj6a2
  • Chain 'B':
    Compound: Beta-2-microglobulin, Contains: Beta-2-microglobulin variant pI 5.3
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • cloning artifact (0)
    Domains in SCOPe 2.01: d2gj6b_
  • Chain 'C':
    Compound: Modified HTLV-1 TAX (Y5K-IBA) peptide, chain C
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2GJ6 (0-8)
  • Chain 'D':
    Compound: A6-Tcr
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • GB 1QSF_D (0-193)
    Domains in SCOPe 2.01: d2gj6d1, d2gj6d2
  • Chain 'E':
    Compound: A6-Tcr
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • GB 1QSE_E (2-243)
    Domains in SCOPe 2.01: d2gj6e1, d2gj6e2
  • Heterogens: SO4, 3IB, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2gj6A (A:)
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
fqkwaavvvpsgqeqrytchvqheglpkpltlrwe

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2gj6B (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2gj6D (D:)
keveqnsgplsvpegaiaslnctysdrgsqsffwyrqysgkspelimsiysngdkedgrf
taqlnkasqyvsllirdsqpsdsatylcavttdswgklqfgagtqvvvtpdiqnpdpavy
qlrdskssdksvclftdfdsqtnvsqskdsdvyitdktvldmrsmdfksnsavawsnksd
facanafnnsiipedtffps

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2gj6E (E:)
nagvtqtpkfqvlktgqsmtlqcaqdmnheymswyrqdpgmglrlihysvgagitdqgev
pngynvsrsttedfplrllsaapsqtsvyfcasrpglaggrpeqyfgpgtrltvtedlkn
vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvstdpqplke
qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
wgrad

    Sequence, based on observed residues (ATOM records): (download) 
    >2gj6E (E:)
gvtqtpkfqvlktgqsmtlqcaqdmnheymswyrqdpgmglrlihysvgagitdqgevpn
gynvsrsttedfplrllsaapsqtsvyfcasrpglaggrpeqyfgpgtrltvtedlknvf
ppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvstdpqplkeqp
alndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawg
rad