PDB entry 2g9h

View 2g9h on RCSB PDB site
Description: Crystal Structure of Staphylococcal Enterotoxin I (SEI) in Complex with a Human MHC class II Molecule
Class: immune system
Keywords: Immune System, Superantigen, Zn, HLA clasII molecule
Deposited on 2006-03-06, released 2006-07-11
The last revision prior to the SCOP 1.75 freeze date was dated 2006-08-15, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.215
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla class II histocompatibility antigen, dr alpha chain
    Species: HOMO SAPIENS
    Gene: HLA-DRA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2g9ha1, d2g9ha2
  • Chain 'B':
    Compound: HLA class II histocompatibility antigen, DRB1-1 beta chain
    Species: HOMO SAPIENS
    Gene: HLA-DRB1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2g9hb1, d2g9hb2
  • Chain 'C':
    Compound: Hemagglutinin
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: extracellular enterotoxin type I
    Species: Staphylococcus aureus
    Database cross-references and differences (RAF-indexed):
    • Uniprot O85383
      • see remark 999 (23-24)
      • see remark 999 (30)
      • see remark 999 (40)
      • see remark 999 (113)
      • see remark 999 (143)
      • see remark 999 (162)
      • see remark 999 (171)
      • see remark 999 (186)
    Domains in SCOP 1.75: d2g9hd1, d2g9hd2
  • Heterogens: ZN, SO4, EPE, DIO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2g9hA (A:)
ikeehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgal
aniavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvt
wlrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
da

    Sequence, based on observed residues (ATOM records): (download) 
    >2g9hA (A:)
ehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgalani
avdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtwlr
ngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwefd

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2g9hB (B:)
gdtrprflwqlkfechffngtervrllerciynqeesvrfdsdvgeyravtelgrpdaey
wnsqkdlleqrraavdtycrhnygvgesftvqrrvepkvtvypsktqplqhhnllvcsvs
gfypgsievrwfrngqeekagvvstgliqngdwtfqtlvmletvprsgevytcqvehpsv
tspltvewra

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2g9hD (D:)
qgdigvgnlrnfytkhdyidlkglidknlpsanqlefstgindlisesnnwdeiskfkgk
kldifgidyngpckskymyggatlsgqylnsarkipinlwvngkhktistdkistnkklv
taqeidvklrrylqeeyniyghnstgkgkeygykskfysgfnkgkvlfhlndeksfsydl
fytgdgvpvsflkiyednkiiesekfhldveisyvdsn

    Sequence, based on observed residues (ATOM records): (download) 
    >2g9hD (D:)
igvgnlrnfytkhdyidlkglidknlpsanqlefstgindlisesnnwdeiskfkgkkld
ifgidyngpckskymyggatlsgqylnsarkipinlwvngkhktistdkistnkklvtaq
eidvklrrylqeeyniyghnstgkgkeygykskfysgfnkgkvlfhlndeksfsydlfyt
gdgvpvsflkiyednkiiesekfhldveisyvd