PDB entry 2g7k

View 2g7k on RCSB PDB site
Description: Structure of the Light Chain of Botulinum Neurotoxin, Serotype A Bound to small Molecule Inhibitors
Class: hydrolase
Keywords: Botulinum neurotoxin, zinc protease, SNAP25, HYDROLASE
Deposited on 2006-02-28, released 2006-08-15
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.223
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Botulinum neurotoxin type A
    Species: Clostridium botulinum [TaxId:1491]
    Gene: botA, atx, bna
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q45894 (1-End)
      • initiating methionine (0)
    Domains in SCOPe 2.05: d2g7ka_
  • Chain 'B':
    Compound: Botulinum neurotoxin type A
    Species: Clostridium botulinum [TaxId:1491]
    Gene: botA, atx, bna
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q45894 (1-End)
      • initiating methionine (0)
    Domains in SCOPe 2.05: d2g7kb_

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2g7kA (A:)
mfvnkqfnykdpvngvdiayikipnagqmqpvkafkihnkiwviperdtftnpeegdlnp
ppeakqvpvsyydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwggs
tidtelkvidtncinviqpdgsyrseelnlviigpsadiiqfecksfghdvlnltrngyg
stqyirfspdftfgfeeslevdtnpllgagkfatdpavtlahelihaehrlygiainpnr
vfkvntnayyemsglevsfeelrtfgghdakfidslqenefrlyyynkfkdvastlnkak
siigttaslqymknvfkekyllsedtsgkfsvdklkfdklykmlteiytednfvnffkvi
nrktylnfdkavfrinivpdenytikdgfnlkganlstnfngqnteinsrnftrlknftg
lfefy

    Sequence, based on observed residues (ATOM records): (download) 
    >2g7kA (A:)
mfvnkqfnykdpvngvdiayikipnagqmqpvkafkihnkiwviperdtftnpeegdlnv
syydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwggstidtelkvi
dtncinviqpdgsyrseelnlviigpsadiiqfecksfghdvlnltrngygstqyirfsp
dftfgfeeslevdtnpllgagkfatdpavtlahelihaehrlygiainpnrvfkvntsgl
evsfeelrtfgghdakfidslqenefrlyyynkfkdvastlnkaksiigttaslqymknv
fkekyllsedtsgkfsvdklkfdklykmlteiytednfvnffkvinrktylnfdkavfri
nivpdenytikdgfnlkganlstnfngqnteinsrnftrlk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2g7kB (B:)
mfvnkqfnykdpvngvdiayikipnagqmqpvkafkihnkiwviperdtftnpeegdlnp
ppeakqvpvsyydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwggs
tidtelkvidtncinviqpdgsyrseelnlviigpsadiiqfecksfghdvlnltrngyg
stqyirfspdftfgfeeslevdtnpllgagkfatdpavtlahelihaehrlygiainpnr
vfkvntnayyemsglevsfeelrtfgghdakfidslqenefrlyyynkfkdvastlnkak
siigttaslqymknvfkekyllsedtsgkfsvdklkfdklykmlteiytednfvnffkvi
nrktylnfdkavfrinivpdenytikdgfnlkganlstnfngqnteinsrnftrlknftg
lfefy

    Sequence, based on observed residues (ATOM records): (download) 
    >2g7kB (B:)
mfvnkqfnykdpvngvdiayikipnagqmqpvkafkihnkiwviperdtftnpeegdlns
yydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwggstidtelkvid
tncinviqpdgsyrseelnlviigpsadiiqfecksfghdvlnltrngygstqyirfspd
ftfgfeeslevdtnpllgagkfatdpavtlahelihaehrlygiainpnrvfkvntglev
sfeelrtfgghdakfidslqenefrlyyynkfkdvastlnkaksiigttaslqymknvfk
ekyllsedtsgkfsvdklkfdklykmlteiytednfvnffkvinrktylnfdkavfrini
vpdenytikdgfnlkganlstnfngqnteinsrnftrlk