PDB entry 2g7k

View 2g7k on RCSB PDB site
Description: Structure of the Light Chain of Botulinum Neurotoxin, Serotype A Bound to small Molecule Inhibitors
Class: hydrolase
Keywords: Botulinum neurotoxin, zinc protease, SNAP25, HYDROLASE
Deposited on 2006-02-28, released 2006-08-15
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.223
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Botulinum neurotoxin type A
    Species: Clostridium botulinum [TaxId:1491]
    Gene: botA, atx, bna
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q45894 (1-End)
      • initiating methionine (0)
    Domains in SCOPe 2.04: d2g7ka_
  • Chain 'B':
    Compound: Botulinum neurotoxin type A
    Species: Clostridium botulinum [TaxId:1491]
    Gene: botA, atx, bna
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q45894 (1-End)
      • initiating methionine (0)
    Domains in SCOPe 2.04: d2g7kb_

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2g7kA (A:)
    mfvnkqfnykdpvngvdiayikipnagqmqpvkafkihnkiwviperdtftnpeegdlnp
    ppeakqvpvsyydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwggs
    tidtelkvidtncinviqpdgsyrseelnlviigpsadiiqfecksfghdvlnltrngyg
    stqyirfspdftfgfeeslevdtnpllgagkfatdpavtlahelihaehrlygiainpnr
    vfkvntnayyemsglevsfeelrtfgghdakfidslqenefrlyyynkfkdvastlnkak
    siigttaslqymknvfkekyllsedtsgkfsvdklkfdklykmlteiytednfvnffkvi
    nrktylnfdkavfrinivpdenytikdgfnlkganlstnfngqnteinsrnftrlknftg
    lfefy
    

    Sequence, based on observed residues (ATOM records): (download)
    >2g7kA (A:)
    mfvnkqfnykdpvngvdiayikipnagqmqpvkafkihnkiwviperdtftnpeegdlnv
    syydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwggstidtelkvi
    dtncinviqpdgsyrseelnlviigpsadiiqfecksfghdvlnltrngygstqyirfsp
    dftfgfeeslevdtnpllgagkfatdpavtlahelihaehrlygiainpnrvfkvntsgl
    evsfeelrtfgghdakfidslqenefrlyyynkfkdvastlnkaksiigttaslqymknv
    fkekyllsedtsgkfsvdklkfdklykmlteiytednfvnffkvinrktylnfdkavfri
    nivpdenytikdgfnlkganlstnfngqnteinsrnftrlk
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2g7kB (B:)
    mfvnkqfnykdpvngvdiayikipnagqmqpvkafkihnkiwviperdtftnpeegdlnp
    ppeakqvpvsyydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwggs
    tidtelkvidtncinviqpdgsyrseelnlviigpsadiiqfecksfghdvlnltrngyg
    stqyirfspdftfgfeeslevdtnpllgagkfatdpavtlahelihaehrlygiainpnr
    vfkvntnayyemsglevsfeelrtfgghdakfidslqenefrlyyynkfkdvastlnkak
    siigttaslqymknvfkekyllsedtsgkfsvdklkfdklykmlteiytednfvnffkvi
    nrktylnfdkavfrinivpdenytikdgfnlkganlstnfngqnteinsrnftrlknftg
    lfefy
    

    Sequence, based on observed residues (ATOM records): (download)
    >2g7kB (B:)
    mfvnkqfnykdpvngvdiayikipnagqmqpvkafkihnkiwviperdtftnpeegdlns
    yydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwggstidtelkvid
    tncinviqpdgsyrseelnlviigpsadiiqfecksfghdvlnltrngygstqyirfspd
    ftfgfeeslevdtnpllgagkfatdpavtlahelihaehrlygiainpnrvfkvntglev
    sfeelrtfgghdakfidslqenefrlyyynkfkdvastlnkaksiigttaslqymknvfk
    ekyllsedtsgkfsvdklkfdklykmlteiytednfvnffkvinrktylnfdkavfrini
    vpdenytikdgfnlkganlstnfngqnteinsrnftrlk