PDB entry 2g45

View 2g45 on RCSB PDB site
Description: Co-crystal structure of znf ubp domain from the deubiquitinating enzyme isopeptidase T (isot) in complex with ubiquitin
Class: hydrolase
Keywords: Ubiquitin, Zinc Finger, deubiquitinating enzyme, HYDROLASE
Deposited on 2006-02-21, released 2006-04-04
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.99 Å
R-factor: 0.229
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin carboxyl-terminal hydrolase 5
    Species: Homo sapiens [TaxId:9606]
    Gene: USP5, ISOT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2g45a_
  • Chain 'B':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2g45b_
  • Chain 'D':
    Compound: Ubiquitin carboxyl-terminal hydrolase 5
    Species: Homo sapiens [TaxId:9606]
    Gene: USP5, ISOT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2g45d_
  • Chain 'E':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2g45e_
  • Heterogens: ZN, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2g45A (A:)
kqevqawdgevrqvskhafslkqldnparippcgwkcskcdmrenlwlnltdgsilcgrr
yfdgsggnnhavehyretgyplavklgtitpdgadvysydeddmvldpslaehlshfgid
mlkmqktdk

    Sequence, based on observed residues (ATOM records): (download) 
    >2g45A (A:)
vrqvskhafslkqldnparippcgwkcskcdmrenlwlnltdgsilcgrryfdgsggnnh
avehyretgyplavklgtitpdgadvysydeddmvldpslaehlshfgidmlkmqkt

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2g45B (B:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrgg

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2g45D (D:)
kqevqawdgevrqvskhafslkqldnparippcgwkcskcdmrenlwlnltdgsilcgrr
yfdgsggnnhavehyretgyplavklgtitpdgadvysydeddmvldpslaehlshfgid
mlkmqktdk

    Sequence, based on observed residues (ATOM records): (download) 
    >2g45D (D:)
vrqvskhafslkqldnparippcgwkcskcdmrenlwlnltdgsilcgrryfdgsggnnh
avehyretgyplavklgtitpdgadvysydeddmvldpslaehlshfgidmlkmqkt

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2g45E (E:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrgg