PDB entry 2g25

View 2g25 on RCSB PDB site
Description: E. Coli Pyruvate Dehydrogenase Phosphonolactylthiamin Diphosphate Complex
Class: oxidoreductase
Keywords: plthdp, phosphonolactylthiamin diphosphate, pyruvate dehydrogenase e1 component
Deposited on 2006-02-15, released 2006-04-25
The last revision prior to the SCOP 1.73 freeze date was dated 2006-06-13, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.185
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pyruvate dehydrogenase E1 component
    Species: Escherichia coli
    Gene: aceE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2g25a1, d2g25a2, d2g25a3
  • Chain 'B':
    Compound: Pyruvate dehydrogenase E1 component
    Species: Escherichia coli
    Gene: aceE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2g25b1, d2g25b2, d2g25b3
  • Heterogens: MG, PO4, TDK, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2g25A (A:)
serfpndvdpietrdwlqaiesvireegveraqylidqllaearkggvnvaagtgisnyi
ntipveeqpeypgnlelerrirsairwnaimtvlraskkdlelgghmasfqssatiydvc
fnhffrarneqdggdlvyfqghispgvyaraflegrltqeqldnfrqevhgnglssyphp
klmpefwqfptvsmglgpigaiyqakflkylehrglkdtskqtvyaflgdgemdepeskg
aitiatrekldnlvfvincnlqrldgpvtgngkiinelegifegagwnvikvmwgsrwde
llrkdtsgkliqlmnetvdgdyqtfkskdgayvrehffgkypetaalvadwtdeqiwaln
rgghdpkkiyaafkkaqetkgkatvilahtikgygmgdaaegkniahqvkkmnmdgvrhi
rdrfnvpvsdadieklpyitfpegseehtylhaqrqklhgylpsrqpnfteklelpslqd
fgalleeqskeisttiafvralnvmlknksikdrlvpiiadeartfgmeglfrqigiysp
ngqqytpqdreqvayykedekgqilqeginelgagcswlaaatsystnnlpmipfyiyys
mfgfqrigdlcwaagdqqargfliggtsgrttlngeglqhedghshiqsltipncisydp
ayayevavimhdglermygekqenvyyyittlnenyhmpampegaeegirkgiykletie
gskgkvqllgsgsilrhvreaaeilakdygvgsdvysvtsftelardgqdcerwnmlhpl
etprvpyiaqvmndapavastdymklfaeqvrtyvpaddyrvlgtdgfgrsdsrenlrhh
fevdasyvvvaalgelakrgeidkkvvadaiakfnidadkvnprla

    Sequence, based on observed residues (ATOM records): (download) 
    >2g25A (A:)
isnyintipveeqpeypgnlelerrirsairwnaimtvlraskkdlelgghmasfqssat
iydvcfnhffrarneqdggdlvyfqghispgvyaraflegrltqeqldnfrqevhgngls
syphpklmpefwqfptvsmglgpigaiyqakflkylehrglkdtskqtvyaflgdgemde
peskgaitiatrekldnlvfvincnlqrldgpvtgngkiinelegifegagwnvikvmwg
srwdellrkdtsgkliqlmnetvdgdyqtfkskdgayvrehffgkypetaalvadwtdeq
iwalnrgghdpkkiyaafkkaqetkgkatvilahtikgygmgdaaegkniahqvkkmnmd
gvrhirdrfnvpvsdadieklpyitfpegseehtylhaqrqklhgylpsrqpnfteklel
pslqdfgalleeqskeisttiafvralnvmlknksikdrlvpiiadeartfgmeglfrqi
giyspngqqytpqdreqvayykedekgqilqeginelgagcswlaaatsystnnlpmipf
yiyysmfgfqrigdlcwaagdqqargfliggtsgrttlngeglqhedghshiqsltipnc
isydpayayevavimhdglermygekqenvyyyittlnenyhmpampegaeegirkgiyk
letiegskgkvqllgsgsilrhvreaaeilakdygvgsdvysvtsftelardgqdcerwn
mlhpletprvpyiaqvmndapavastdymklfaeqvrtyvpaddyrvlgtdgfgrsdsre
nlrhhfevdasyvvvaalgelakrgeidkkvvadaiakfnidadkvnprla

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2g25B (B:)
serfpndvdpietrdwlqaiesvireegveraqylidqllaearkggvnvaagtgisnyi
ntipveeqpeypgnlelerrirsairwnaimtvlraskkdlelgghmasfqssatiydvc
fnhffrarneqdggdlvyfqghispgvyaraflegrltqeqldnfrqevhgnglssyphp
klmpefwqfptvsmglgpigaiyqakflkylehrglkdtskqtvyaflgdgemdepeskg
aitiatrekldnlvfvincnlqrldgpvtgngkiinelegifegagwnvikvmwgsrwde
llrkdtsgkliqlmnetvdgdyqtfkskdgayvrehffgkypetaalvadwtdeqiwaln
rgghdpkkiyaafkkaqetkgkatvilahtikgygmgdaaegkniahqvkkmnmdgvrhi
rdrfnvpvsdadieklpyitfpegseehtylhaqrqklhgylpsrqpnfteklelpslqd
fgalleeqskeisttiafvralnvmlknksikdrlvpiiadeartfgmeglfrqigiysp
ngqqytpqdreqvayykedekgqilqeginelgagcswlaaatsystnnlpmipfyiyys
mfgfqrigdlcwaagdqqargfliggtsgrttlngeglqhedghshiqsltipncisydp
ayayevavimhdglermygekqenvyyyittlnenyhmpampegaeegirkgiykletie
gskgkvqllgsgsilrhvreaaeilakdygvgsdvysvtsftelardgqdcerwnmlhpl
etprvpyiaqvmndapavastdymklfaeqvrtyvpaddyrvlgtdgfgrsdsrenlrhh
fevdasyvvvaalgelakrgeidkkvvadaiakfnidadkvnprla

    Sequence, based on observed residues (ATOM records): (download) 
    >2g25B (B:)
isnyintipveeqpeypgnlelerrirsairwnaimtvlraskkdlelgghmasfqssat
iydvcfnhffrarneqdggdlvyfqghispgvyaraflegrltqeqldnfrqevhgngls
syphpklmpefwqfptvsmglgpigaiyqakflkylehrglkdtskqtvyaflgdgemde
peskgaitiatrekldnlvfvincnlqrldgpvtgngkiinelegifegagwnvikvmwg
srwdellrkdtsgkliqlmnetvdgdyqtfkskdgayvrehffgkypetaalvadwtdeq
iwalnrgghdpkkiyaafkkaqetkgkatvilahtikgygmgdaaegkniahqvkkmnmd
gvrhirdrfnvpvsdadieklpyitfpegseehtylhaqrqklhgylpsrqpnfteklel
pslqdfgalleeqskeisttiafvralnvmlknksikdrlvpiiadeartfgmeglfrqi
giyspngqqytpqdreqvayykedekgqilqeginelgagcswlaaatsystnnlpmipf
yiyysmfgfqrigdlcwaagdqqargfliggtsgrttlngeglqhedghshiqsltipnc
isydpayayevavimhdglermygekqenvyyyittlnenyhmpampegaeegirkgiyk
letiegskgkvqllgsgsilrhvreaaeilakdygvgsdvysvtsftelardgqdcerwn
mlhpletprvpyiaqvmndapavastdymklfaeqvrtyvpaddyrvlgtdgfgrsdsre
nlrhhfevdasyvvvaalgelakrgeidkkvvadaiakfnidadkvnprla