PDB entry 2g1i

View 2g1i on RCSB PDB site
Description: Crystal Structure of Pyruvate Decarboxylase from Kluyveromyces lactis
Class: Lyase
Keywords: dimer of dimers, asymmetric active sites, substrate activation, Lyase
Deposited on 2006-02-14, released 2006-09-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-01-27, with a file datestamp of 2009-01-23.
Experiment type: XRAY
Resolution: 2.26 Å
R-factor: 0.159
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: pyruvate decarboxylase
    Species: KLUYVEROMYCES LACTIS [TaxId:28985]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2g1ia1, d2g1ia2, d2g1ia3
  • Chain 'B':
    Compound: pyruvate decarboxylase
    Species: KLUYVEROMYCES LACTIS [TaxId:28985]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2g1ib1, d2g1ib2, d2g1ib3
  • Chain 'C':
    Compound: pyruvate decarboxylase
    Species: KLUYVEROMYCES LACTIS [TaxId:28985]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2g1ic1, d2g1ic2, d2g1ic3
  • Chain 'D':
    Compound: pyruvate decarboxylase
    Species: KLUYVEROMYCES LACTIS [TaxId:28985]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2g1id1, d2g1id2, d2g1id3
  • Heterogens: MG, TPP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2g1iA (A:)
mseitlgrylferlkqvevqtifglpgdfnlslldniyevpgmrwagnanelnaayaadg
yarlkgmsciittfgvgelsalngiagsyaehvgvlhvvgvpsvssqakqlllhhtlgng
dftvfhrmssnisettamitdintapaeidrcirttyvsqrpvylglpanlvdltvpasl
ldtpidlslkpndpeaeeevienvlqlikeaknpviladaccsrhdakaetkklidltqf
pafvtpmgkgsidekhprfggvyvgtlsspavkeavesadlvlsvgallsdfntgsfsys
yktknivefhsdytkirsatfpgvqmkfalqklltkvadaakgykpvpvpsepehneava
dstplkqewvwtqvgeflregdvvitetgtsafginqthfpnntygisqvlwgsigfttg
atlgaafaaeeidpkkrvilfigdgslqltvqeistmirwglkpylfvlnndgytierli
hgetaqynciqnwqhlellptfgakdyeavrvsttgewnklttdekfqdntrirlievml
ptmdapsnlvkqaqltaatnakn

    Sequence, based on observed residues (ATOM records): (download) 
    >2g1iA (A:)
seitlgrylferlkqvevqtifglpgdfnlslldniyevpgmrwagnanelnaayaadgy
arlkgmsciittfgvgelsalngiagsyaehvgvlhvvgvpsvshhtlgngdftvfhrms
snisettamitdintapaeidrcirttyvsqrpvylglpanlvdltvpaslldtpidlsl
kpndpeaeeevienvlqlikeaknpviladaccsrhdakaetkklidltqfpafvtpmgk
gsidekhprfggvyvgtlsspavkeavesadlvlsvgalltknivefhsdytkirsatfp
gvqmkfalqklltkvadaakgykpvpvpsepehneavadstplkqewvwtqvgeflregd
vvitetgtsafginqthfpnntygisqvlwgsigfttgatlgaafaaeeidpkkrvilfi
gdgslqltvqeistmirwglkpylfvlnndgytierlihgetaqynciqnwqhlellptf
gakdyeavrvsttgewnklttdekfqdntrirlievmlptmdapsnlvkqaqltaatnak

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2g1iB (B:)
mseitlgrylferlkqvevqtifglpgdfnlslldniyevpgmrwagnanelnaayaadg
yarlkgmsciittfgvgelsalngiagsyaehvgvlhvvgvpsvssqakqlllhhtlgng
dftvfhrmssnisettamitdintapaeidrcirttyvsqrpvylglpanlvdltvpasl
ldtpidlslkpndpeaeeevienvlqlikeaknpviladaccsrhdakaetkklidltqf
pafvtpmgkgsidekhprfggvyvgtlsspavkeavesadlvlsvgallsdfntgsfsys
yktknivefhsdytkirsatfpgvqmkfalqklltkvadaakgykpvpvpsepehneava
dstplkqewvwtqvgeflregdvvitetgtsafginqthfpnntygisqvlwgsigfttg
atlgaafaaeeidpkkrvilfigdgslqltvqeistmirwglkpylfvlnndgytierli
hgetaqynciqnwqhlellptfgakdyeavrvsttgewnklttdekfqdntrirlievml
ptmdapsnlvkqaqltaatnakn

    Sequence, based on observed residues (ATOM records): (download) 
    >2g1iB (B:)
seitlgrylferlkqvevqtifglpgdfnlslldniyevpgmrwagnanelnaayaadgy
arlkgmsciittfgvgelsalngiagsyaehvgvlhvvgvpsvhhtlgngdftvfhrmss
nisettamitdintapaeidrcirttyvsqrpvylglpanlvdltvpaslldtpidlslk
pndpeaeeevienvlqlikeaknpviladaccsrhdakaetkklidltqfpafvtpmgkg
sidekhprfggvyvgtlsspavkeavesadlvlsvgallsdfntgsfsysyktknivefh
sdytkirsatfpgvqmkfalqklltkvadaakgykpvpvpsepehneavadstplkqewv
wtqvgeflregdvvitetgtsafginqthfpnntygisqvlwgsigfttgatlgaafaae
eidpkkrvilfigdgslqltvqeistmirwglkpylfvlnndgytierlihgetaqynci
qnwqhlellptfgakdyeavrvsttgewnklttdekfqdntrirlievmlptmdapsnlv
kqaq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2g1iC (C:)
mseitlgrylferlkqvevqtifglpgdfnlslldniyevpgmrwagnanelnaayaadg
yarlkgmsciittfgvgelsalngiagsyaehvgvlhvvgvpsvssqakqlllhhtlgng
dftvfhrmssnisettamitdintapaeidrcirttyvsqrpvylglpanlvdltvpasl
ldtpidlslkpndpeaeeevienvlqlikeaknpviladaccsrhdakaetkklidltqf
pafvtpmgkgsidekhprfggvyvgtlsspavkeavesadlvlsvgallsdfntgsfsys
yktknivefhsdytkirsatfpgvqmkfalqklltkvadaakgykpvpvpsepehneava
dstplkqewvwtqvgeflregdvvitetgtsafginqthfpnntygisqvlwgsigfttg
atlgaafaaeeidpkkrvilfigdgslqltvqeistmirwglkpylfvlnndgytierli
hgetaqynciqnwqhlellptfgakdyeavrvsttgewnklttdekfqdntrirlievml
ptmdapsnlvkqaqltaatnakn

    Sequence, based on observed residues (ATOM records): (download) 
    >2g1iC (C:)
seitlgrylferlkqvevqtifglpgdfnlslldniyevpgmrwagnanelnaayaadgy
arlkgmsciittfgvgelsalngiagsyaehvgvlhvvgvpsvtlgngdftvfhrmssni
settamitdintapaeidrcirttyvsqrpvylglpanlvdltvpaslldtpidlslkpn
dpeaeeevienvlqlikeaknpviladaccsrhdakaetkklidltqfpafvtpmgkgsi
dekhprfggvyvgtlsspavkeavesadlvlsvgallsdfntgsfsysyktknivefhsd
ytkirsatfpgvqmkfalqklltkvadaakgykpvpvpsepehneavadstplkqewvwt
qvgeflregdvvitetgtsafginqthfpnntygisqvlwgsigfttgatlgaafaaeei
dpkkrvilfigdgslqltvqeistmirwglkpylfvlnndgytierlihgetaqynciqn
wqhlellptfgakdyeavrvsttgewnklttdekfqdntrirlievmlptmdapsnlvkq
aqlt

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2g1iD (D:)
mseitlgrylferlkqvevqtifglpgdfnlslldniyevpgmrwagnanelnaayaadg
yarlkgmsciittfgvgelsalngiagsyaehvgvlhvvgvpsvssqakqlllhhtlgng
dftvfhrmssnisettamitdintapaeidrcirttyvsqrpvylglpanlvdltvpasl
ldtpidlslkpndpeaeeevienvlqlikeaknpviladaccsrhdakaetkklidltqf
pafvtpmgkgsidekhprfggvyvgtlsspavkeavesadlvlsvgallsdfntgsfsys
yktknivefhsdytkirsatfpgvqmkfalqklltkvadaakgykpvpvpsepehneava
dstplkqewvwtqvgeflregdvvitetgtsafginqthfpnntygisqvlwgsigfttg
atlgaafaaeeidpkkrvilfigdgslqltvqeistmirwglkpylfvlnndgytierli
hgetaqynciqnwqhlellptfgakdyeavrvsttgewnklttdekfqdntrirlievml
ptmdapsnlvkqaqltaatnakn

    Sequence, based on observed residues (ATOM records): (download) 
    >2g1iD (D:)
seitlgrylferlkqvevqtifglpgdfnlslldniyevpgmrwagnanelnaayaadgy
arlkgmsciittfgvgelsalngiagsyaehvgvlhvvgvpsvdftvfhrmssnisetta
mitdintapaeidrcirttyvsqrpvylglpanlvdltvpaslldtpidlslkpndpeae
eevienvlqlikeaknpviladaccsrhdakaetkklidltqfpafvtpmgkgsidekhp
rfggvyvgtlsspavkeavesadlvlsvgallsdfntgsfsysyktknivefhsdytkir
satfpgvqmkfalqklltkvadaakgykpvpvpsepehneavadstplkqewvwtqvgef
lregdvvitetgtsafginqthfpnntygisqvlwgsigfttgatlgaafaaeeidpkkr
vilfigdgslqltvqeistmirwglkpylfvlnndgytierlihgetaqynciqnwqhle
llptfgakdyeavrvsttgewnklttdekfqdntrirlievmlptmdapsnlvkqaqlta
atnak