PDB entry 2fo1

View 2fo1 on RCSB PDB site
Description: Crystal Structure of the CSL-Notch-Mastermind ternary complex bound to DNA
Class: gene regulation/signalling protein/DNA
Keywords: beta-barrel, PROTEIN-DNA COMPLEX, DOUBLE HELIX, ankyrin repeat
Deposited on 2006-01-12, released 2006-03-21
The last revision prior to the SCOP 1.73 freeze date was dated 2006-04-04, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 3.12 Å
R-factor: 0.273
AEROSPACI score: 0.09 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lin-12 and glp-1 phenotype protein 1, isoform b
    Species: Caenorhabditis elegans
    Gene: LAG-1
    Database cross-references and differences (RAF-indexed):
    • GB AAM98006 (Start-476)
    Domains in SCOP 1.73: d2fo1a1, d2fo1a2, d2fo1a3
  • Chain 'B':
    Compound: 5'-d(*tp*tp*ap*cp*tp*gp*tp*gp*gp*gp*ap*ap*ap*gp*a)-3'
    Species: synthetic, synthetic
  • Chain 'C':
    Compound: 5'-d(*ap*ap*tp*cp*tp*tp*tp*cp*cp*cp*ap*cp*ap*gp*t)-3'
    Species: synthetic, synthetic
  • Chain 'D':
    Compound: Protein lag-3
    Species: Caenorhabditis elegans
    Gene: sel-8, lag-3
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Lin-12 protein
    Species: Caenorhabditis elegans
    Gene: lin-12
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14585
      • modified residue (10)
      • modified residue (17)
      • modified residue (20)
      • modified residue (161)
      • modified residue (170)
      • modified residue (185)
      • modified residue (213-214)
      • modified residue (217)
      • modified residue (235)
      • modified residue (239)
      • modified residue (291)
      • modified residue (317)
      • modified residue (329)

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2fo1A (A:)
gplgsgdsvqsltsdrmidflsnkekyecvisifhakvaqksygnekrffcpppciylig
qgwklkkdrvaqlyktlkasaqkdaaiendpiheqqatelvayigigsdtserqqldfst
gkvrhpgdqrqdpniydycaaktlyisdsdkrkyfdlnaqffygcgmeiggfvsqrikvi
skpskkkqsmkntdckylciasgtkvalfnrlrsqtvstrylhvegnafhasstkwgaft
ihlfdderglqetdnfavrdgfvyygsvvklvdsvtgialprlrirkvdkqqvildascs
eepvsqlhkcafqmidnelvylclshdkiiqhqatainehrhqindgaawtiistdkaey
rffeamgqvanpispcpvvgslevdghgeasrvelhgrdfkpnlkvwfgatpvettfrse
eslhcsippvsqvrneqthwmftnrttgdvevpislvrddgvvyssgltfsyksler

    Sequence, based on observed residues (ATOM records): (download) 
    >2fo1A (A:)
vqsltsdrmidflsnkekyecvisifhakvaqksygnekrffcpppciyligqgwklkkd
rvaqlyktlkasaiheqqatelvayigigsdtserqqldfstgkvrhpniydycaaktly
isdsdkrkyfdlnaqffygcgmeiggfvsqrikviskpskkdckylciasgtkvalfnrl
rsqtvstrylhvegnafhasstkwgaftihlfddednfavrdgfvyygsvvklvdsvtgi
alprlrirkvdkqqvildascseepvsqlhkcafqmidnelvylclshdkiiqhqatain
ehrhqindgaawtiistdkaeyrffeamgqvanpispcpvvgslevdghgeasrvelhgr
dfkpnlkvwfgatpvettfrseeslhcsippvsqvrneqthwmftnrttgdvevpislvr
ddgvvyssgltfsyksler

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.