PDB entry 2fjh

View 2fjh on RCSB PDB site
Description: Structure of the B20-4 Fab, a phage derived Fab fragment, in complex with VEGF
Class: hormone/growth factor/immune system
Keywords: VEGF, Fab, Protein Fab complex, Cystine knot
Deposited on 2006-01-02, released 2006-02-07
The last revision prior to the SCOP 1.75 freeze date was dated 2006-11-07, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: 0.2
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fab fragment light chain
    Species: HOMO SAPIENS
  • Chain 'B':
    Compound: Fab fragment heavy chain
    Species: HOMO SAPIENS
  • Chain 'H':
    Compound: Fab fragment heavy chain
    Species: HOMO SAPIENS
  • Chain 'L':
    Compound: Fab fragment light chain
    Species: HOMO SAPIENS
  • Chain 'V':
    Compound: Vascular Endothelial Growth Factor A
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2fjhv1
  • Chain 'W':
    Compound: Vascular Endothelial Growth Factor A
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2fjhw1

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    No sequence available.

  • Chain 'V':
    Sequence, based on SEQRES records: (download)
    >2fjhV (V:)
    gqnhhevvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggccndegle
    cvpteesnitmqimrikphqgqhigemsflqhnkcecrpkkd
    

    Sequence, based on observed residues (ATOM records): (download)
    >2fjhV (V:)
    hevvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggccndeglecvpt
    eesnitmqimrikphqgqhigemsflqhnkcecrpkkd
    

  • Chain 'W':
    Sequence, based on SEQRES records: (download)
    >2fjhW (W:)
    gqnhhevvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggccndegle
    cvpteesnitmqimrikphqgqhigemsflqhnkcecrpkkd
    

    Sequence, based on observed residues (ATOM records): (download)
    >2fjhW (W:)
    evvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggccndeglecvpte
    esnitmqimrikphqgqhigemsflqhnkcecrpkkd