PDB entry 2fap

View 2fap on RCSB PDB site
Description: the structure of the immunophilin-immunosuppressant fkbp12-(c16)-ethoxy rapamycin complex interacting with huma
Class: complex (isomerase/kinase)
Keywords: FKBP12, FRAP, RAPAMYCIN, COMPLEX (ISOMERASE-KINASE), COMPLEX (ISOMERASE-KINASE) complex
Deposited on 1998-09-22, released 1999-05-18
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-09-18, with a file datestamp of 2013-09-13.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.196
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: fk506-binding protein
  Species: Homo sapiens [TaxId:9606]
  Gene: HUMAN HIPPOCAMPAL CDNA LIBRARY (CLONTECH, PALO ALTO, CA)
  Database cross-references and differences (RAF-indexed):
  • Uniprot P62942 (0-106)
  Domains in SCOPe 2.05: d2fapa_
• Chain 'B':
  Compound: frap
  Species: Homo sapiens [TaxId:9606]
  Gene: HUMAN HIPPOCAMPAL CDNA LIBRARY
  Database cross-references and differences (RAF-indexed):
  • Uniprot P42345 (0-93)
  Domains in SCOPe 2.05: d2fapb_
• Heterogens: RAD, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2fapA (A:)
  gvqvetispgdgrtfpkrgqtcvvhytgmledgkkfdssrdrnkpfkfmlgkqevirgwe
  egvaqmsvgqrakltispdyaygatghpgiipphatlvfdvellkle
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2fapB (B:)
  vailwhemwhegleeasrlyfgernvkgmfevleplhammergpqtlketsfnqaygrdl
  meaqewcrkymksgnvkdltqawdlyyhvfrris