PDB entry 2f3d

View 2f3d on RCSB PDB site
Description: Mechanism of displacement of a catalytically essential loop from the active site of fructose-1,6-bisphosphatase
Class: hydrolase
Keywords: allosteric regulation, allostery, fructose-1,6-bisphosphatase, FBPase, enzyme catalysis, loop displacement
Deposited on 2005-11-21, released 2006-04-25
The last revision prior to the SCOP 1.73 freeze date was dated 2006-04-25, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 1.83 Å
R-factor: 0.222
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fructose-1,6-bisphosphatase 1
    Species: SUS SCROFA
    Gene: FBP1, FBP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00636 (Start-337)
      • engineered (10)
    Domains in SCOP 1.73: d2f3da1
  • Heterogens: F6P, PO4, ZN, AMP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2f3dA (A:)
mtdqaafdtndvtltrfvmeegrkargtgemtqllnslctavkaistavrkagiahlygi
agstnvtgdqvkkldvlsndlvinvlkssfatcvlvseedknaiivepekrgkyvvcfdp
ldgssnidclvsigtifgiyrknstdepsekdalqpgrnlvaagyalygsatmlvlamvn
gvncfmldpaigefilvdrdvkikkkgsiysinegyakefdpaiteyiqrkkfppdnsap
ygaryvgsmvadvhrtlvyggifmypankkspkgklrllyecnpmayvmekagglattgk
eavldivptdihqrapiilgspedvtelleiyqkhaak

    Sequence, based on observed residues (ATOM records): (download) 
    >2f3dA (A:)
dvtltrfvmeegrkargtgemtqllnslctavkaistavrkagiahlygiagstnvtgdq
vkkldvlsndlvinvlkssfatcvlvseedknaiivepekrgkyvvcfdpldgssnidcl
vsigtifgiyrknstdepsekdalqpgrnlvaagyalygsatmlvlamvngvncfmldpa
igefilvdrdvkikkkgsiysinegyakefdpaiteyiqrkkfppdnsapygaryvgsmv
advhrtlvyggifmypankkspkgklrllyecnpmayvmekagglattgkeavldivptd
ihqrapiilgspedvtelleiyqkhaak