PDB entry 2f10

View 2f10 on RCSB PDB site
Description: Crystal Structure of the Human Sialidase Neu2 in Complex with Peramivir inhibitor
Class: hydrolase
Keywords: sialidase, neuraminidase, influenza virus, peramivir
Deposited on 2005-11-14, released 2006-11-21
The last revision prior to the SCOP 1.73 freeze date was dated 2006-11-21, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.215
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Sialidase 2
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2f10a1
  • Heterogens: PO4, BCZ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2f10A (A:)
gsmaslpvlqkesvfqsgahayripallylpgqqsllafaeqraskkdehaelivlrrgd
ydapthqvqwqaqevvaqarldghrsmnpcplydaqtgtlflffiaipgqvteqqqlqtr
anvtrlcqvtstdhgrtwssprdltdaaigpayrewstfavgpghclqlndrarslvvpa
yayrklhpiqrpipsafcflshdhgrtwarghfvaqdtlecqvaevetgeqrvvtlnars
hlrarvqaqstndgldfqesqlvkklvepppqgcqgsvisfpsprsgpgspaqwllythp
thswqradlgaylnprppapeawsepvllakgscaysdlqsmgtgpdgsplfgclyeand
yeeivflmftlkqafpaeylpq

    Sequence, based on observed residues (ATOM records): (download) 
    >2f10A (A:)
slpvlqkesvfqsgahayripallylpgqqsllafaeqraaelivlrrgdydapthqvqw
qaqevvaqarldghrsmnpcplydaqtgtlflffiaipgranvtrlcqvtstdhgrtwss
prdltdaaigpayrewstfavgpghclqlndrarslvvpayayrklhiqrpipsafcfls
hdhgrtwarghfvaqdtlecqvaeveqrvvtlnarshlrarvqaqstndgldfqesqlvk
klvepppqgcqgsvisfpspraqwllythpthswqradlgaylnprppapeawsepvlla
kgscaysdlqsmgtgpdgsplfgclyeandyeeivflmftlkqafpaey