PDB entry 2f0z

View 2f0z on RCSB PDB site
Description: Crystal Structure of the Human Sialidase Neu2 in Complex with Zanamivir inhibitor
Class: hydrolase
Keywords: SIALIDASE, NEURAMINIDASE, INFLUENZA VIRUS, ZANAMIVIR, hydrolase
Deposited on 2005-11-14, released 2006-11-21
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.192
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Sialidase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2f0za_
  • Heterogens: ZMR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2f0zA (A:)
    gsmaslpvlqkesvfqsgahayripallylpgqqsllafaeqraskkdehaelivlrrgd
    ydapthqvqwqaqevvaqarldghrsmnpcplydaqtgtlflffiaipgqvteqqqlqtr
    anvtrlcqvtstdhgrtwssprdltdaaigpayrewstfavgpghclqlndrarslvvpa
    yayrklhpiqrpipsafcflshdhgrtwarghfvaqdtlecqvaevetgeqrvvtlnars
    hlrarvqaqstndgldfqesqlvkklvepppqgcqgsvisfpsprsgpgspaqwllythp
    thswqradlgaylnprppapeawsepvllakgscaysdlqsmgtgpdgsplfgclyeand
    yeeivflmftlkqafpaeylpq
    

    Sequence, based on observed residues (ATOM records): (download)
    >2f0zA (A:)
    slpvlqkesvfqsgahayripallylpgqqsllafaeqraelivlrrgdydapthqvqwq
    aqevvaqarldghrsmnpcplydaqtgtlflffiaipgqvteqqqlqtranvtrlcqvts
    tdhgrtwssprdltdaaigpayrewstfavgpghclqlndrarslvvpayayrklrpips
    afcflshdhgrtwarghfvaqdtlecqvaeveqrvvtlnarshlrarvqaqstndgldfq
    esqlvkklvepppqgcqgsvisfpsprpaqwllythpthswqradlgaylnprppapeaw
    sepvllakgscaysdlqsmgtgpdgsplfgclyeandyeeivflmftlkqafpaey