PDB entry 2ex4

View 2ex4 on RCSB PDB site
Description: Crystal Structure of Human methyltransferase AD-003 in complex with S-adenosyl-L-homocysteine
Class: Transferase
Keywords: methyltransferase, Structural Genomics, SGC, Structural Genomics Consortium
Deposited on 2005-11-07, released 2005-11-15
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.197
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: adrenal gland protein AD-003
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9BV86 (19-239)
      • cloning artifact (16-18)
    Domains in SCOPe 2.05: d2ex4a1
  • Chain 'B':
    Compound: adrenal gland protein AD-003
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9BV86 (19-239)
      • cloning artifact (16-18)
    Domains in SCOPe 2.05: d2ex4b_
  • Heterogens: SAH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ex4A (A:)
mgsshhhhhhssglvprgstseviedekqfyskaktywkqipptvdgmlggyghissidi
nssrkflqrflregpnktgtscaldcgagigritkrlllplfrevdmvditedflvqakt
ylgeegkrvrnyfccglqdftpepdsydviwiqwvighltdqhlaeflrrckgslrpngi
ivikdnmaqegvilddvdssvcrdldvvrriicsaglsllaeerqenlpdeiyhvysfal
r

    Sequence, based on observed residues (ATOM records): (download) 
    >2ex4A (A:)
rgstseviedekqfyskaktywkqipptvdgmlggyghissidinssrkflqrflrktgt
scaldcgagigritkrlllplfrevdmvditedflvqaktylgeegkrvrnyfccglqdf
tpepdsydviwiqwvighltdqhlaeflrrckgslrpngiivikdnmaqegvilddvdss
vcrdldvvrriicsaglsllaeerqenlpdeiyhvysfalr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2ex4B (B:)
mgsshhhhhhssglvprgstseviedekqfyskaktywkqipptvdgmlggyghissidi
nssrkflqrflregpnktgtscaldcgagigritkrlllplfrevdmvditedflvqakt
ylgeegkrvrnyfccglqdftpepdsydviwiqwvighltdqhlaeflrrckgslrpngi
ivikdnmaqegvilddvdssvcrdldvvrriicsaglsllaeerqenlpdeiyhvysfal
r

    Sequence, based on observed residues (ATOM records): (download) 
    >2ex4B (B:)
rgstseviedekqfyskaktywkqipptvdgmlggyghissidinssrkflqrflrktgt
scaldcgagigritkrlllplfrevdmvditedflvqaktylgeegkrvrnyfccglqdf
tpepdsydviwiqwvighltdqhlaeflrrckgslrpngiivikdnmaqegvilddvdss
vcrdldvvrriicsaglsllaeerqenlpdeiyhvysfalr