PDB entry 2ec9

View 2ec9 on RCSB PDB site
Description: Crystal structure analysis of human Factor VIIa , Souluble tissue factor complexed with BCX-3607
Class: blood clotting
Keywords: protein-cofactor complex, FVIIa and souluble tissue factor, inhibitor, BLOOD CLOTTING
Deposited on 2007-02-13, released 2008-02-19
The last revision prior to the SCOP 1.75 freeze date was dated 2008-02-19, with a file datestamp of 2008-02-15.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.242
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'H':
  Compound: Coagulation factor VII
  Species: HOMO SAPIENS
  Database cross-references and differences (RAF-indexed):
  • Uniprot P08709 (0-253)
  Domains in SCOP 1.75: d2ec9h1
• Chain 'L':
  Compound: Coagulation factor VII
  Species: HOMO SAPIENS
  Database cross-references and differences (RAF-indexed):
  • Uniprot P08709 (0-141)
  Domains in SCOP 1.75: d2ec9l1, d2ec9l2, d2ec9l3
• Chain 'T':
  Compound: tissue factor
  Species: HOMO SAPIENS
  Database cross-references and differences (RAF-indexed):
  • Uniprot P13726 (0-74)
• Chain 'U':
  Compound: tissue factor
  Species: HOMO SAPIENS
  Database cross-references and differences (RAF-indexed):
  • Uniprot P13726 (0-119)
• Heterogens: GLC, FUC, CA, 24X, HOH

PDB Chain Sequences:

• Chain 'H':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2ec9H (H:)
  ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
  lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
  lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
  sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
  seprpgvllrapfp
  

  
  
• Chain 'L':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2ec9L (L:)
  anafleelrpgslereckeeqcsfeeareifkdaertklfwisysdgdqcasspcqnggs
  ckdqlqsyicfclpafegrncethkddqlicvnenggceqycsdhtgtkrscrchegysl
  ladgvsctptveypcgkipile
  

  
  
• Chain 'T':
  No sequence available.
  
  
• Chain 'U':
  No sequence available.