PDB entry 2e0a

View 2e0a on RCSB PDB site
Description: Crystal structure of human pyruvate dehydrogenase kinase 4 in complex with AMPPNP
Class: transferase
Keywords: PDK4, kinase, ATP-binding, Structural Genomics, NPPSFA, National Project on Protein Structural and Functional Analyses, RIKEN Structural Genomics/Proteomics Initiative, RSGI, TRANSFERASE
Deposited on 2006-10-03, released 2007-10-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-11-23, with a file datestamp of 2011-11-18.
Experiment type: XRAY
Resolution: 1.86 Å
R-factor: 0.196
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pyruvate dehydrogenase kinase isozyme 4
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2e0aa1, d2e0aa2
  • Chain 'B':
    Compound: Pyruvate dehydrogenase kinase isozyme 4
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2e0ab1, d2e0ab2
  • Heterogens: MG, ANP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2e0aA (A:)
gpvprevehfsryspsplsmkqlldfgsenacertsfaflrqelpvrlanilkeidilpt
qlvntssvqlvkswyiqslmdlvefhekspddqkalsdfvdtlikvrnrhhnvvptmaqg
iieykdactvdpvtnqnlqyfldrfymnristrmlmnqhilifsdsqtgnpshigsidpn
cdvvavvqdafecsrmlcdqyylsspelkltqvngkfpdqpihivyvpshlhhmlfelfk
namratvehqenqpsltpievivvlgkedltikisdrgggvplriidrlfsytystaptp
vmdnsrnaplagfgyglpisrlyakyfqgdlnlyslsgygtdaiiylkalssesieklpv
fnksafkhyqmsseaddwcipsrepknlakevam

    Sequence, based on observed residues (ATOM records): (download) 
    >2e0aA (A:)
vprevehfsryspsplsmkqlldfgscertsfaflrqelpvrlanilkeidilptqlvnt
ssvqlvkswyiqslmdlvefhekspddqkalsdfvdtlikvrnrhhnvvptmaqgiieyk
dactvdpvtnqnlqyfldrfymnristrmlmnqhilifsdsqtgnpshigsidpncdvva
vvqdafecsrmlcdqyylsspelkltqvngkfpdqpihivyvpshlhhmlfelfknamra
tvehqenqpsltpievivvlgkedltikisdrgggvplriidrlfsytystaptpnapla
gfgyglpisrlyakyfqgdlnlyslsgygtdaiiylkalssesieklpvfnksafkhy

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2e0aB (B:)
gpvprevehfsryspsplsmkqlldfgsenacertsfaflrqelpvrlanilkeidilpt
qlvntssvqlvkswyiqslmdlvefhekspddqkalsdfvdtlikvrnrhhnvvptmaqg
iieykdactvdpvtnqnlqyfldrfymnristrmlmnqhilifsdsqtgnpshigsidpn
cdvvavvqdafecsrmlcdqyylsspelkltqvngkfpdqpihivyvpshlhhmlfelfk
namratvehqenqpsltpievivvlgkedltikisdrgggvplriidrlfsytystaptp
vmdnsrnaplagfgyglpisrlyakyfqgdlnlyslsgygtdaiiylkalssesieklpv
fnksafkhyqmsseaddwcipsrepknlakevam

    Sequence, based on observed residues (ATOM records): (download) 
    >2e0aB (B:)
vprevehfsryspsplsmkqlldfgscertsfaflrqelpvrlanilkeidilptqlvnt
ssvqlvkswyiqslmdlvefhekspddqkalsdfvdtlikvrnrhhnvvptmaqgiieyk
dactvdpvtnqnlqyfldrfymnristrmlmnqhilifsdsqtgnpshigsidpncdvva
vvqdafecsrmlcdqyylsspelkltqvngkfpdqpihivyvpshlhhmlfelfknamra
tvehqenqpsltpievivvlgkedltikisdrgggvplriidrlfsytystaplagfgyg
lpisrlyakyfqgdlnlyslsgygtdaiiylkalssesieklpvfnksafkhy