PDB entry 2d9q

View 2d9q on RCSB PDB site
Description: Crystal Structure of the Human GCSF-Receptor Signaling Complex
Class: signaling protein/cytokine
Keywords: cytokine, ligand-receptor complex
Deposited on 2005-12-12, released 2006-02-07
The last revision prior to the SCOP 1.75 freeze date was dated 2006-06-20, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.253
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: csf3
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2d9qa1
  • Chain 'B':
    Compound: granulocyte colony-stimulating factor receptor
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99062
      • engineered (77)
      • engineered (162)
      • engineered (227)
    Domains in SCOP 1.75: d2d9qb1, d2d9qb2, d2d9qb3
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2d9qA (A:)
    tplgpasslpqsfllkcleqvrkiqgdgaalqeklcatyklchpeelvllghslgipwap
    lsscpsqalqlagclsqlhsglflyqgllqalegispelgptldtlqldvadfattiwqq
    meelgmapalqptqgampafasafqrraggvlvashlqsflevsyrvlrhlaqp
    

    Sequence, based on observed residues (ATOM records): (download)
    >2d9qA (A:)
    sslpqsfllkcleqvrkiqgdgaalqeklcatyklchpeelvllghslgipwaplsscps
    qalqlagclsqlhsglflyqgllqalegispelgptldtlqldvadfattiwqqmeelgm
    apalqptqgampafasafqrraggvlvashlqsflevsyrvlrhlaqp
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2d9qB (B:)
    ecghisvsapivhlgdpitasciikqncshldpepqilwrlgaelqpggrqqrlsdgtqe
    siitlphlnhtqaflscslnwgnslqildqvelragyppaiphnlsclmnlttsslicqw
    epgpethlptsftlksfksrgncqtqgdsildcvpkdgqshcsiprkhlllyqnmgiwvq
    aenalgtsmspqlcldpmdvvkleppmlrtmdpspeaappqagclqlswepwqpglhinq
    kcelrhkpqrgeaswalvgplplealqyelcgllpataytlqircirwplpghwsdwsps
    lelrtteraaapr
    

    Sequence, based on observed residues (ATOM records): (download)
    >2d9qB (B:)
    cghisvsapivhlgdpitasciikqncshldpepqilwrlgaelqpggrqqrlsdgtqes
    iitlphlnhtqaflscslnwgnslqildqvelragyppaiphnlsclmnlttsslicqwe
    pgpethlptsftlksfksrgncqtqgdsildcvpkdgqshcsiprkhlllyqnmgiwvqa
    enalgtsmspqlcldpmdvvkleppmlrtmdpqagclqlswepwqpglhinqkcelrhkp
    qrgeaswalvgplplealqyelcgllpataytlqircirwplpghwsdwspslelrtte