SCOPe 2.06: Structural Classification of Proteins

PDB entry 2cw0

View 2cw0 on RCSB PDB site
Description: Crystal structure of Thermus thermophilus RNA polymerase holoenzyme at 3.3 angstroms resolution
Class: transferase
Keywords: RNA polymerase holoenzyme, transcription, bent-bridge helix, TRANSFERASE
Deposited on 2005-06-15, released 2005-09-20
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-09-05, with a file datestamp of 2012-08-31.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: 0.282
AEROSPACI score: 0.06 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: DNA-directed RNA polymerase alpha chain
Species: Thermus thermophilus [TaxId:274]
Database cross-references and differences (RAF-indexed):
- Uniprot Q5SHR6 (0-End)
Domains in SCOPe 2.06: d2cw0a1, d2cw0a2
Chain 'B':
Compound: DNA-directed RNA polymerase alpha chain
Species: Thermus thermophilus [TaxId:274]
Database cross-references and differences (RAF-indexed):
- Uniprot Q5SHR6 (0-End)
Domains in SCOPe 2.06: d2cw0b1, d2cw0b2
Chain 'C':
Compound: DNA-directed RNA polymerase beta chain
Species: Thermus thermophilus [TaxId:300852]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8RQE9 (0-1118)
Domains in SCOPe 2.06: d2cw0c1
Chain 'D':
Compound: DNA-directed RNA polymerase beta' chain
Species: Thermus thermophilus [TaxId:300852]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8RQE8
Domains in SCOPe 2.06: d2cw0d1
Chain 'E':
Compound: RNA polymerase omega chain
Species: Thermus thermophilus [TaxId:274]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8RQE7
Domains in SCOPe 2.06: d2cw0e1
Chain 'F':
Compound: RNA polymerase sigma factor rpoD
Species: Thermus thermophilus [TaxId:262724]
Database cross-references and differences (RAF-indexed):
- Uniprot Q5SKW1 (Start-422)
Domains in SCOPe 2.06: d2cw0f1, d2cw0f2, d2cw0f3
Chain 'K':
Compound: DNA-directed RNA polymerase alpha chain
Species: Thermus thermophilus [TaxId:274]
Database cross-references and differences (RAF-indexed):
- Uniprot Q5SHR6 (0-End)
Domains in SCOPe 2.06: d2cw0k1, d2cw0k2
Chain 'L':
Compound: DNA-directed RNA polymerase alpha chain
Species: Thermus thermophilus [TaxId:274]
Database cross-references and differences (RAF-indexed):
- Uniprot Q5SHR6 (0-End)
Domains in SCOPe 2.06: d2cw0l1, d2cw0l2
Chain 'M':
Compound: DNA-directed RNA polymerase beta chain
Species: Thermus thermophilus [TaxId:300852]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8RQE9 (0-1118)
Domains in SCOPe 2.06: d2cw0m1
Chain 'N':
Compound: DNA-directed RNA polymerase beta' chain
Species: Thermus thermophilus [TaxId:300852]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8RQE8
Domains in SCOPe 2.06: d2cw0n1
Chain 'O':
Compound: RNA polymerase omega chain
Species: Thermus thermophilus [TaxId:274]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8RQE7
Domains in SCOPe 2.06: d2cw0o1
Chain 'P':
Compound: RNA polymerase sigma factor rpoD
Species: Thermus thermophilus [TaxId:262724]
Database cross-references and differences (RAF-indexed):
- Uniprot Q5SKW1 (Start-422)
Domains in SCOPe 2.06: d2cw0p1, d2cw0p2, d2cw0p3
Heterogens: ZN, MG

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>2cw0A (A:)
mldsklkapvftvrtqgreygefvleplergfgvtlgnplrrillssipgtavtsvyied
vlhefstipgvkedvveiilnlkelvvrflnpslqtvtlllkaegpkevkardflpvadv
eimnpdlhiatleeggrlnmevrvdrgvgyvpaekhgikdrinaipvdavfspvrrvafq
vedtrlgqrtdldkltlriwtdgsvtplealnqaveilrehltyfsnpqaaavaapeeak
epeappeqeeeldlpleelglstrvlhslkeegiesvrallalnlkdlknipgigersle
eikealekkgftlke