PDB entry 2c6m

View 2c6m on RCSB PDB site
Description: Crystal structure of the human CDK2 complexed with the triazolopyrimidine inhibitor
Class: transferase
Keywords: transferase, serine/threonine protein kinase, cdk2, ATP-binding, cell cycle, mitosis, phosphorylation, triazolopyrimidine inhibitor, cell division, kinase, nucleotide-binding
Deposited on 2005-11-10, released 2005-12-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-09-16, with a file datestamp of 2015-09-11.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2c6ma_
  • Heterogens: DT5, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2c6mA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >2c6mA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirlvpstaireisllkelnhpnivkl
    ldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhr
    dlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyystavdi
    wslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarq
    dfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl